Evidence map›Paper›PMID 32340310›Full record

ArticleMolecules (Basel, Switzerland)2020

Technetium-Radiolabeled Mannose-Functionalized Gold Nanoparticles as Nanoprobes for Sentinel Lymph Node Detection.

Oscar J Estudiante-Mariquez, Andrés Rodríguez-Galván, David Ramírez-Hernández, Flavio F Contreras-Torres, Luis A Medina

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Comparative Study of a Series ofMolecules (Basel, Switzerland) · 2021
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Oscar J Estudiante-MariquezUnidad de Investigación Biomédica en Cáncer INCan-UNAM, Instituto Nacional de Cancerología, Cd. México 14080, Mexico.
Andrés Rodríguez-GalvánCarrera de Biología, Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Estado de México 54090, Mexico.ORCID 0000-0001-7208-773X
David Ramírez-HernándezUnidad de Investigación Biomédica en Cáncer INCan-UNAM, Instituto Nacional de Cancerología, Cd. México 14080, Mexico.
Flavio F Contreras-TorresEscuela de Ingeniería y Ciencias, Tecnologico de Monterrey, Nuevo León 64849, Mexico.ORCID 0000-0003-2375-131X
Luis A MedinaUnidad de Investigación Biomédica en Cáncer INCan-UNAM, Instituto Nacional de Cancerología, Cd. México 14080, Mexico.ORCID 0000-0001-9301-5823
Instituto Nacional de Cancerología · MXAutonomous University of Tlaxcala · MXTecnológico de Monterrey · MX

Funding

Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México DGAPA-IN104919
6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) are considered valuable nanomaterials for the design of radiolabeled nanoprobes for single-photon emission computed tomography (SPECT) imaging. Radiolabeled and functionalized AuNPs could improve lymphatic mapping by enhancing the radioactive signaling of individual particles in the sentinel node. In this study, an alternative method for functionalizing commercial AuNps with mannose is described. The chemical derivatization and biofunctionalization of AuNPs were performed with lipoic acid and mannose, respectively. Several levels of mannose were tested; the thiolate hydrazinonicotinamide-glycine-glycine-cysteine (HYNIC) molecule was also used for

Indexed as

GoldMannoseMetal NanoparticlesTechnetiumAnimalsHumansMaleNeoplasmsRadiopharmaceuticalsRatsSentinel Lymph NodeTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedX-Ray MicrotomographyGoldMannoseRadiopharmaceuticalsTechnetium99mTcgold nanoparticlesmannosesentinel lymph nodeSPECT

Identifiers

PMID32340310
PMCPMC7221884
OpenAlexW3020680440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.