Evidence map›Paper›PMID 32340294›Full record

ArticleSensors (Basel, Switzerland)2020

KickStat: A Coin-Sized Potentiostat for High-Resolution Electrochemical Analysis.

Orlando S Hoilett, Jenna F Walker, Bethany M Balash, Nicholas J Jaras, Sriram Boppana, Jacqueline C Linnes

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 87 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Orlando S HoilettWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-9091-349X
Jenna F WalkerWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Bethany M BalashWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Nicholas J JarasSchool of Electrical and Computer Engineering, Purdue University, West Lafayette, IN 47907, USA.
Sriram BoppanaWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0001-6369-3455
Jacqueline C LinnesWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0003-4962-0908
Purdue University West Lafayette · US

Funding

CSRD VA 1NIH HHS 108380
6 · The paper itself

Abstract

The demand for wearable and point-of-care devices has led to an increase in electrochemical sensor development to measure an ever-increasing array of biological molecules. In order to move from the benchtop to truly portable devices, the development of new biosensors requires miniaturized instrumentation capable of making highly sensitive amperometric measurements. To meet this demand, we have developed KickStat, a miniaturized potentiostat that combines the small size of the integrated Texas Instruments LMP91000 potentiostat chip (Texas Instruments, Dallas, TX, USA) with the processing power of the ARM Cortex-M0+ SAMD21 microcontroller (Microchip Technology, Chandler, AZ, USA) on a custom-designed 21.6 mm by 20.3 mm circuit board. By incorporating onboard signal processing via the SAMD21, we achieve 1 mV voltage increment resolution and an instrumental limit of detection of 4.5 nA in a coin-sized form factor. This elegant engineering solution allows for high-resolution electrochemical analysis without requiring extensive circuitry. We measured the faradaic current of an anti-cocaine aptamer using cyclic voltammetry and square wave voltammetry and demonstrated that KickStat's response was within 0.6% of a high-end benchtop potentiostat. To further support others in electrochemical biosensors development, we have made KickStat's design and firmware available in an online GitHub repository.

Indexed as

amperometricbiosensorselectrochemistrylow-costminiaturizedopen-sourcepoint-of-carevoltammetrywearable

Identifiers

PMID32340294
PMCPMC7219484
OpenAlexW3018049995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.