Evidence map›Paper›PMID 32340193›Full record

ArticleCancers2020

Enhancing Antitumor Efficacy of Heavily Vascularized Tumors by RAMBO Virus through Decreased Tumor Endothelial Cell Activation.

Mitra Nair, Maninder Khosla, Yoshihiro Otani, Margaret Yeh, Flora Park, Toshihiko Shimizu, Jin Muk Kang, Chelsea Bolyard, Jun-Ge Yu, Yeshavanth Kumar Banasavadi-Siddegowda and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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  6. Applications of Intravital Imaging in Cancer Immunotherapy.Bioengineering (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Mitra NairDepartment of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Maninder KhoslaDepartment of Otolaryngology-Head and Neck Surgery, James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Yoshihiro OtaniDepartment of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0000-0002-1615-5125
Margaret YehDepartment of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Flora ParkDepartment of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Toshihiko ShimizuDepartment of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0000-0002-2594-234X
Jin Muk KangDepartment of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Chelsea BolyardComprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Columbus, OH 43202, USA.
Jun-Ge YuDepartment of Otolaryngology-Head and Neck Surgery, James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Yeshavanth Kumar Banasavadi-SiddegowdaSurgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
Gonzalo LopezDepartment of Surgery, Division of Surgical Oncology, James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Balveen KaurDepartment of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Raphael E PollockDepartment of Surgery, Division of Surgical Oncology, James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Tae Jin LeeDepartment of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Matthew OldDepartment of Otolaryngology-Head and Neck Surgery, James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Ji Young YooDepartment of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
The University of Texas Health Science Center at Houston · USThe Ohio State University Wexner Medical Center · USNational Institutes of Health · USThe Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute · US

Funding

American Cancer Society RSG-19-185-01-MPC
6 · The paper itself

Abstract

Vascularization is a common pathology for many solid tumors, and therefore anti-angiogenic strategies are being investigated as a therapeutic target for treatment. Numerous studies are also being conducted regarding the effects of oncolytic viruses, including Imlygic

Indexed as

angiogenesisoncolytic herpes simplex virus-1 (oHSV)rapid antiangiogenesis mediated by oncolytic virus (RAMBO)soft tissue sarcoma (STS)tumor microenvironment (TME)vasculostatin (Vstat120)

Identifiers

PMID32340193
PMCPMC7225935
OpenAlexW3020139951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.