ReviewAntioxidants (Basel, Switzerland)2020
Diet and Mental Health: Review of the Recent Updates on Molecular Mechanisms.
Review in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
136 citing papers in PubMed, 8 syntheses or guidelines pooled it, 244 citations in OpenAlex.
- Pooled it
- Impact of probiotics on sleep quality and mood states in patients with insomnia: a systematic review and meta-analysis.Frontiers in microbiology · 2025Pooled it
- The Impact ofCurrent neuropharmacology · 2025Pooled it
- Fish consumption, cognitive impairment and dementia: an updated dose-response meta-analysis of observational studies.Aging clinical and experimental research · 2024Pooled it
- Association of sleep duration and risk of mental disorder: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- Pooled it
- Pooled it
- Association between dietary inflammatory index and cognitive impairment: A meta-analysis.Frontiers in aging neuroscience · 2022Pooled it
- The Moderating Role of Dietary Quality and Dietary Fibre Intake on the Mood Effects of Positive Expressive Writing: A Pilot Study.Nutrients · 2024Trial
- Effects of Probiotic NVP-1704 on Mental Health and Sleep in Healthy Adults: An 8-Week Randomized, Double-Blind, Placebo-Controlled Trial.Nutrients · 2021Trial
- From Gut to Mind: Impact of Probiotics on Depression, Anxiety, Mood, Gut Microbiota, Sleep and Stress-A Systematic Review of RCTs.Annals of neurosciences · 2026Review
- Adipose Tissue-Central Nervous System Axis in Obesity: Molecular Mechanisms, Inflammation, and Nutritional and Technological Implications.Metabolites · 2026Review
- Article
- Loneliness, Aloneness, and Adherence to the Mediterranean Diet in Southern Italian Individuals.Nutrients · 2026Article
- A digital twin framework for predicting and simulating type 2 diabetes onset using retrospective lifestyle data.Frontiers in digital health · 2026Article
- Chronic Inflammation and Neuroprogression in the Pathophysiology in Major Depression.Advances in experimental medicine and biology · 2026Review
- Comparative evaluation of gut health, inflammatory factors, and sleep quality among shift workers: A cross-sectional study.Journal of education and health promotion · 2026Article
- Consumption of ultra-processed foods is associated with cognitive status in elderly patients.Frontiers in nutrition · 2026Article
- The Art of Nanoimmunobiotechnomedicine in Depression Management.Advanced pharmaceutical bulletin · 2025Review
- Association between ultra-processed food intake, night eating behavior, and sleep quality: a cross-sectional study from Türkiye.Health and quality of life outcomes · 2025Article
76 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last decades, there has been a substantial increase in the prevalence of mental health disorders, including an increased prevalence of depression, anxiety, cognitive, and sleep disorders. Diet and its bioactive components have been recognized among the modifiable risk factors, possibly influencing their pathogenesis. This review aimed to summarize molecular mechanisms underlying the putative beneficial effects toward brain health of different dietary factors, such as micro- and macronutrient intake and habits, such as feeding time and circadian rhythm. The role of hormonal homeostasis in the context of glucose metabolism and adiponectin regulation and its impact on systemic and neuro-inflammation has also been considered and deepened. In addition, the effect of individual bioactive molecules exerting antioxidant activities and acting as anti-inflammatory agents, such as omega-3 fatty acids and polyphenols, considered beneficial for the central nervous system via modulation of adult neurogenesis, synaptic and neuronal plasticity, and microglia activation has been summarized. An overview of the regulation of the gut-brain axis and its effect on the modulation of systemic inflammation and oxidative stress has been provided. Finally, the impact of bioactive molecules on inflammation and oxidative stress and its association with brain health has been summarized.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.