Evidence map›Paper›PMID 32340014›Full record

ArticlePhysics in medicine and biology2020

Practical joint reconstruction of activity and attenuation with autonomous scaling for time-of-flight PET.

Yusheng Li, Samuel Matej, Joel S Karp

Open access · hybridAbstract read
In one paragraph

Article in Physics in medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Total-body PET: a new paradigm for molecular imaging.The British journal of radiology · 2022
    Review
  5. Abbreviated scan protocols to captureEuropean journal of nuclear medicine and molecular imaging · 2022
    Article
  6. Review
  7. 2D feasibility study of joint reconstruction of attenuation and activity in limited angle TOF-PET.IEEE transactions on radiation and plasma medical sciences · 2021
    Article
  8. Modified kernel MLAA using autoencoder for PET-enabled dual-energy CT.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yusheng LiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, United States of America.ORCID 0000-0002-2678-1103
Samuel MatejDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, United States of America.
Joel S KarpDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, United States of America.
University of Pennsylvania · US

Funding

EXPLORER: Changing the Molecular Imaging Paradigm with Total Body PETR01CA206187 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BADAWI, RAMSEY D., CHERRY, SIMON R · 2015 to 2019
$15.5M
Time-of-Flight PET for Improved Whole-Body ImagingR01CA113941 · NCI · UNIVERSITY OF PENNSYLVANIA · PI JOEL S KARP, Suleman Surti · 2006 to 2026
$9.8M
Development and application of 4D TOF reconstruction for quantitative PET imagingR01EB023274 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI MATEJ, SAMUEL · 2017 to 2020
$2.2M
Area B: Multi-Tracer Volumetric PET (MTV-PET) to Measure Tumor Glutamine and Glucose Metabolic Rates in a Single Imaging SessionR33CA225310 · NCI · UNIVERSITY OF PENNSYLVANIA · PI KARP, JOEL S, MANKOFF, DAVID A. · 2017 to 2017
$1.4M
NCI NIH HHS R01 CA113941NCI NIH HHS R01 CA206187NCI NIH HHS R33 CA225310NIBIB NIH HHS R01 EB023274
6 · The paper itself

Abstract

Recent research has showed that attenuation images can be determined from emission data, jointly with activity images, up to a scaling constant when utilizing the time-of-flight (TOF) information. We aim to develop practical CT-less joint reconstruction for clinical TOF PET scanners to obtain quantitatively accurate activity and attenuation images. In this work, we present a joint reconstruction of activity and attenuation based on MLAA (maximum likelihood reconstruction of attenuation and activity) with autonomous scaling determination and joint TOF scatter estimation from TOF PET data. Our idea for scaling is to use a selected volume of interest (VOI) in a reconstructed attenuation image with known attenuation, e.g. a liver in patient imaging. First, we construct a unit attenuation medium which has a similar, though not necessarily the same, support to the imaged emission object. All detectable LORs intersecting the unit medium have an attenuation factor of e

Indexed as

AlgorithmsPhantoms, ImagingWhole Body ImagingComputer SimulationHumansImage Processing, Computer-AssistedPositron-Emission Tomography

Identifiers

PMID32340014
PMCPMC8383745
OpenAlexW2947694996

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.