Evidence map›Paper›PMID 32339999›Full record

Observational studyJMIR mHealth and uHealth2020

Mobile Health Daily Life Monitoring for Parkinson Disease: Development and Validation of Ecological Momentary Assessments.

Jeroen Habets, Margot Heijmans, Christian Herff, Claudia Simons, Albert Fg Leentjens, Yasin Temel, Mark Kuijf, Pieter Kubben

Abstract readObservational Study
In one paragraph

Observational study in JMIR mHealth and uHealth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Perspective: Depression in Persons with Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026
    Review
  5. Article
  6. Article
  7. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeroen HabetsDepartment of Neurosurgery, School of Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.ORCID 0000-0002-1015-093X
Margot HeijmansDepartment of Neurosurgery, School of Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.ORCID 0000-0002-1628-6336
Christian HerffDepartment of Neurosurgery, School of Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.ORCID 0000-0002-5610-2618
Claudia SimonsDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.ORCID 0000-0002-7637-3589
Albert Fg LeentjensDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.ORCID 0000-0002-7901-571X
Yasin TemelDepartment of Neurosurgery, School of Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.ORCID 0000-0002-3589-5604
Mark KuijfDepartment of Neurology, Maastricht University Medical Center, Maastricht, Netherlands.ORCID 0000-0002-7284-5833
Pieter KubbenDepartment of Neurosurgery, School of Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.ORCID 0000-0002-8059-523X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParkinson disease monitoring is currently transitioning from periodic clinical assessments to continuous daily life monitoring in free-living conditions. Traditional Parkinson disease monitoring methods lack intraday fluctuation detection. Electronic diaries (eDiaries) hold the potential to collect subjective experiences on the severity and burden of motor and nonmotor symptoms in free-living conditions.

objectiveThis study aimed to develop a Parkinson disease-specific eDiary based on ecological momentary assessments (EMAs) and to explore its validation.

methodsAn observational cohort of 20 patients with Parkinson disease used the smartphone-based EMA eDiary for 14 consecutive days without adjusting free-living routines. The eDiary app presented an identical questionnaire consisting of questions regarding affect, context, motor and nonmotor symptoms, and motor performance 7 times daily at semirandomized moments. In addition, patients were asked to complete a morning and an evening questionnaire.

resultsMean affect correlated moderate-to-strong and moderate with motor performance (R=0.38 to 0.75; P<.001) and motor symptom (R=0.34 to 0.50; P<.001) items, respectively. The motor performance showed a weak-to-moderate negative correlation with motor symptoms (R=-0.31 to -0.48; P<.001). Mean group answers given for on-medication conditions vs wearing-off-medication conditions differed significantly (P<.05); however, not enough questionnaires were completed for the wearing-off-medication condition to reproduce these findings on individual levels.

conclusionsWe presented a Parkinson disease-specific EMA eDiary. Correlations between given answers support the internal validity of the eDiary and underline EMA's potential in free-living Parkinson disease monitoring. Careful patient selection and EMA design adjustment to this targeted population and their fluctuations are necessary to generate robust proof of EMA validation in future work. Combining clinical Parkinson disease knowledge with practical EMA experience is inevitable to design and perform studies, which will lead to the successful integration of eDiaries in free-living Parkinson disease monitoring.

Indexed as

Parkinson DiseaseTelemedicineEcological Momentary AssessmentFemaleHumansMaleSmartphoneecological momentary assessmentelectronic diaryexperience sampling methodParkinson’s disease monitoring

Identifiers

PMID32339999
PMCPMC7248801

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.