ArticleClinical biomechanics (Bristol, Avon)2020
Limited fascicle shortening and fascicle rotation may be associated with impaired voluntary force-generating capacity in pennate muscles of chronic stroke survivors.
Article in Clinical biomechanics (Bristol, Avon), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Clinical efficacy of electroacupuncture antagonistic muscles combined with rehabilitation training in the treatment of spastic hemiplegia after stroke: a systematic review and meta-analysis of randomized controlled trials.Frontiers in neurology · 2025Pooled it
- Effect of sit-to-stand-based training on muscle quality in sedentary adults: a randomized controlled trial.PeerJ · 2023Trial
- The correlation between lower limb spasticity and proprioceptive dysfunction in post-stroke patients.Frontiers in neurology · 2025Article
- Individualized muscle architecture and contractile properties of ankle plantarflexors and dorsiflexors in post-stroke individuals.Frontiers in bioengineering and biotechnology · 2024Article
- Article
- Characterization of the Structural and Mechanical Changes of the Biceps Brachii and Gastrocnemius Muscles in the Subacute and Chronic Stage after Stroke.International journal of environmental research and public health · 2023Article
- Changes in muscle-tendon unit length-force characteristics following experimentally induced photothrombotic stroke cannot be explained by changes in muscle belly structure.European journal of applied physiology · 2021Article
- Isolating the energetic and mechanical consequences of imposed reductions in ankle and knee flexion during gait.Journal of neuroengineering and rehabilitation · 2021Article
- Longer electromechanical delay in paretic triceps surae muscles during voluntary isometric plantarflexion torque generation in chronic hemispheric stroke survivors.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2021Article
- Machine learning to extract muscle fascicle length changes from dynamic ultrasound images in real-time.PloS one · 2021Article
- Quantitative Ultrasound to Assess Skeletal Muscles in Post Stroke Spasticity.Journal of central nervous system disease · 2021Review
- Effects of Changes in Ankle Joint Angle on the Relation Between Plantarflexion Torque and EMG Magnitude in Major Plantar Flexors of Male Chronic Stroke Survivors.Frontiers in neurology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMuscle weakness is one of the most common motor impairments after stroke. A variety of progressive muscular changes are reported in chronic stroke survivors, and it is now feasible to consider these changes as an added source of weakness. However, the net contributions of such muscular changes towards muscle weakness have not been fully quantified.
methodsAccordingly, this study aims: (1) to compare muscle architecture of the human medial gastrocnemius between paretic and non-paretic sides in seven chronic hemispheric stroke survivors under passive conditions; (2) to characterize fascicle behavior (i.e., fascicle shortening and fascicle rotation) of the muscle during voluntary isometric contractions; and (3) to assess potential associations between muscle architectural parameters and muscle weakness. Muscle architecture of the medial gastrocnemius (including fascicle length, fascicle pennation angle, and muscle thickness) was characterized using B-mode ultrasonography, and fascicle behavior was then quantified as a function of isometric plantarflexion torque normalized to body mass.
findingsOur experimental results showed that under passive conditions, there was a significant difference in fascicle length and muscle thickness between paretic and non-paretic muscles, but no difference in resting fascicle pennation angle. However, during isometric contraction, both fascicle shortening and fascicle rotation on the paretic side were significantly decreased, compared to the non-paretic side. Moreover, the relative (i.e., paretic/non-paretic) fascicle rotation-shortening ratio (i.e., fascicle rotation per fascicle shortening) was strongly correlated with the relative maximum voluntary isometric plantarflexion torque.
interpretationThis association implies that such fascicle changes could impair the force-generating capacity of the muscle in chronic stroke survivors.
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