ReviewCurrent opinion in insect science2020
Microbiomes as modulators of Drosophila melanogaster homeostasis and disease.
Review in Current opinion in insect science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- A pore-forming toxin monalysin contributes to infection-induced suppression of defecation in female Drosophila.PLoS pathogens · 2026Article
- The effects of dietary iron supplementation on bacterial infections inbioRxiv : the preprint server for biology · 2026Article
- The effects of dietary iron supplementation on bacterial infections in Manduca sexta larval hemolymph.PloS one · 2026Article
- The intracellular symbiont Wolbachia alters Drosophila development and metabolism to buffer against nutritional stress.PLoS genetics · 2025Article
- Stem cell-specific NF-κB is required for stem cell survival and epithelial regeneration upon intestinal damage.Biology open · 2025Article
- Phylogenetic and functional diversity amongmSystems · 2025Article
- Exploring the role of microbiota in mediating sexually dimorphic infection outcomes in mealworm beetles.Biology letters · 2025Article
- Review
- Identification of intestinal mediators ofmBio · 2025Article
- Identification of anFrontiers in cellular and infection microbiology · 2025Article
- Infection with the entomopathogenic nematodes Steinernema alters the Drosophila melanogaster larval microbiome.PloS one · 2025Article
- MprF-mediated immune evasion is necessary for Lactiplantibacillus plantarum resilience in the Drosophila gut during inflammation.PLoS pathogens · 2024Article
- The role of insect gut microbiota in host fitness, detoxification and nutrient supplementation.Antonie van Leeuwenhoek · 2024Review
- Article
- A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan.Neuron · 2023Article
- Resistance to host antimicrobial peptides mediates resilience of gut commensals during infection and aging inProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Gut microbes predominantly act as living beneficial partners rather than raw nutrients.Scientific reports · 2023Article
- Intestinal GCN2 controlseLife · 2023Article
- Decontamination protocols affect the internal microbiota of ticks.Parasites & vectors · 2023Article
- Steroid hormone regulation of innate immunity in Drosophila melanogaster.PLoS genetics · 2023Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Drosophila melanogaster harbors a simple gut microbial community, or microbiome, that regulates several facets of its physiology. As a result, the host employs multiple mechanisms of maintaining control over its microbiome in an effort to promote overall organismal homeostasis. Perturbations to the balance between microbiome and host can result in states of instability or disease, making maintenance of microbial homeostasis a fundamental physiologic aspect of D. melanogaster biology. While the interactions between microbes and their hosts can be direct, particularly in the context of immunity and gut renewal, effects resulting from indirect interactions, such as those between microbiota members, can be equally as important. This review highlights the major ways, in which D. melanogaster regulates microbial homeostasis, the consequences of disruptions to homeostasis, and the different mechanisms, by which the microbiome interacts with its host.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.