Evidence map›Paper›PMID 32339777›Full record

ArticleMedical hypotheses2020

May IL-17 have a role in COVID-19 infection?

Matteo Megna, Maddalena Napolitano, Gabriella Fabbrocini

Abstract readLetter
In one paragraph

Article in Medical hypotheses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Potential relationships between circulating gene expression ofJournal of Zhejiang University. Science. B · 2025
    Article
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  4. Bridging worlds: a narrative review of IL-17 at the crossroads of inflammation and thrombosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
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  17. Hematopoietic responses to SARS-CoV-2 infection.Cellular and molecular life sciences : CMLS · 2022
    Review
  18. Gender affects IL-23 serum levels in the hospitalized COVID-19 infected patients.American journal of clinical and experimental immunology · 2022
    Article
  19. Interleukin-17A (IL-17A): A silent amplifier of COVID-19.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Matteo MegnaSection of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.
Maddalena NapolitanoDepartment of Medicine and Health Science Vincenzo Tiberio, University of Molise, Campobasso, Italy.
Gabriella FabbrociniSection of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BetacoronavirusPandemicsAnimalsAntibodies, Monoclonal, HumanizedCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentCytokine Release SyndromeHumansInfluenza, HumanInterleukin-17Interleukin-6MiceMice, KnockoutModels, ImmunologicalMultiple Organ FailureAntibodies, Monoclonal, HumanizedIl17ra protein, mouseInterleukin-17Interleukin-6ixekizumabReceptors, Interleukin-17

Identifiers

PMID32339777
PMCPMC7175896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.