Evidence map›Paper›PMID 32339610›Full record

ReviewNeuroscience letters2020

Calcium Signaling in Schwann cells.

Dante J Heredia, Claire De Angeli, Camilla Fedi, Thomas W Gould

Abstract readReview
In one paragraph

Review in Neuroscience letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dante J HerediaDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, 89557, United States.
Claire De AngeliDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, 89557, United States.
Camilla FediDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, 89557, United States.
Thomas W GouldDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, 89557, United States. Electronic address: tgould@medicine.nevada.edu.

Funding

Probing the terminal / perisynaptic Schwann cell transcriptome in early stages of motor neuron disease using a RiboTag approach.R21NS107922 · NINDS · UNIVERSITY OF NEVADA RENO · PI GOULD, THOMAS · 2018 to 2019
$392k
NINDS NIH HHS R21 NS107922
6 · The paper itself

Abstract

In addition to providing structural, metabolic and trophic support to neurons, glial cells of the central, peripheral and enteric nervous systems (CNS, PNS, ENS) respond to and regulate neural activity. One of the most well characterized features of this response is an increase of intracellular calcium. Astrocytes at synapses of the CNS, oligodendrocytes along axons of the CNS, enteric glia associated with the cell bodies and axonal varicosities of the ENS, and Schwann cells at the neuromuscular junction (NMJ) and along peripheral nerves of the PNS, all exhibit this response. Recent technical advances have facilitated the imaging of neural activity-dependent calcium responses in large populations of glial cells and thus provided a new tool to evaluate the physiological significance of these responses. This mini-review summarizes the mechanisms and functional role of activity-induced calcium signaling within Schwann cells, including terminal/perisynaptic Schwann cells (TPSCs) at the NMJ and axonal Schwann cells (ASCs) within peripheral nerves.

Indexed as

AnimalsCalcium SignalingCell CommunicationHumansNeurogliaNeuromuscular JunctionNeuronsSchwann CellsactivitycalciumglianeuromuscularSchwann

Identifiers

PMID32339610
PMCPMC7260247

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.