ArticleThe Journal of investigative dermatology2020
Genome-Wide Association Study Identifies Genetic Associations with Perceived Age.
Article in The Journal of investigative dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Nanoparticle-enriched mass spectrometry proteomics in British South Asians identifies links between genetic variants, plasma protein levels and disease risk.Nature genetics · 2026Article
- Transcriptomic profiling of chlorogenic acid and taurine treatment in human skin cells provides insights into cellular senescence mechanisms.Frontiers in molecular biosciences · 2026Article
- Exploring the Causal Relationship and Potential Mediating Mechanisms Between Obesity and Facial Aging: A Two-Sample, Multivariable and Mediation Mendelian Randomization Study.Clinical, cosmetic and investigational dermatology · 2026Article
- Multi-omic underpinnings of heterogeneous aging across multiple organ systems.Cell genomics · 2025Article
- Sedentary lifestyle, physical activity, and aging: evidence from genetic correlation and mendelian randomization.Aging clinical and experimental research · 2025Article
- Assessment of the Influence of UVR in Cutaneous Melanoma.Photodermatology, photoimmunology & photomedicine · 2025Review
- Identification of gene-sun exposure interactions of GWAS-identified variants in perceived facial aging progression.Frontiers in aging · 2025Article
- DNA Methylation-Regulated ZDHHC17 Promotes the Risk of Facial Skin Aging.Clinical, cosmetic and investigational dermatology · 2025Article
- The Causal Relationship Between Skin Microbiota and Facial Aging: A Mendelian Randomization Study.Aesthetic plastic surgery · 2024Article
- Facial aging, cognitive impairment, and dementia risk.Alzheimer's research & therapy · 2024Article
- Article
- Benchmarking Mendelian randomization methods for causal inference using genome-wide association study summary statistics.American journal of human genetics · 2024Article
- Identification of prospective aging drug targets via Mendelian randomization analysis.Aging cell · 2024Article
- Genetic insights into the gut microbiota and risk of facial skin aging: A Mendelian randomization study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Epigenetics insights from perceived facial aging.Clinical epigenetics · 2023Article
- Perceived Age in Patients Exposed to Distinct UV Indexes: A Systematic Review.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2023Review
- Relationships between circulating metabolites and facial skin aging: a Mendelian randomization study.Human genomics · 2023Article
- Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging.Nature aging · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Failure of dermal protection or repair mechanisms might lead to visibly aged skin. The study aimed to identify genetic associations with perceived age. A genome-wide association study was undertaken in 423,992 adult participants of UK Biobank, using questionnaire data on perceived age and genetic data imputed to the Haplotype Reference Consortium imputation panel. The study identified 74 independently associated genetic loci, to our knowledge previously unreported (P < 5 × 10
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.