Evidence map›Paper›PMID 32338626›Full record

ArticleIET nanobiotechnology2020

Preparation and characterisation of silica-based nanoparticles for cisplatin release on cancer brain cells.

Emma Ortiz-Islas, María Elena Manríquez-Ramírez, Amarilis Sosa-Muñoz, Paola Almaguer, Carlos Arias, Patricia Guevara, Gonzalo Hernández-Cortez, Ma Lucinda Aguirre-Cruz

Open access · bronzeAbstract read
In one paragraph

Article in IET nanobiotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Emma Ortiz-IslasNanotechnology Laboratory, National Institute of Neurology and Neurosurgery, Insurgentes Sur 3877, La Fama, 14269 México City, Mexico. emma170@hotmail.com.
María Elena Manríquez-RamírezESIQIE-National Polytechnic Institute, Instituto Politécnico Nacional s/n, Col. Zacatenco, 07738 México City, Mexico.
Amarilis Sosa-MuñozNanotechnology Laboratory, National Institute of Neurology and Neurosurgery, Insurgentes Sur 3877, La Fama, 14269 México City, Mexico.
Paola AlmaguerESIQIE-National Polytechnic Institute, Instituto Politécnico Nacional s/n, Col. Zacatenco, 07738 México City, Mexico.
Carlos AriasESIQIE-National Polytechnic Institute, Instituto Politécnico Nacional s/n, Col. Zacatenco, 07738 México City, Mexico.
Patricia GuevaraNeuroimmunology Laboratory, National Institute of Neurology and Neurosurgery, Insurgentes Sur 3877, La Fama, 14269 México City, Mexico.
Gonzalo Hernández-CortezGerencia de materiales y productos químicos, Instituto Mexicano del Petróleo, Eje Lázaro Cárdenas 152, 07730 México City, Mexico.
Ma Lucinda Aguirre-CruzLaboratory of Neuroimmunoendocrinology, National Institute of Neurology and Neurosurgery, Insurgentes Sur 3877, La Fama, 14269 México City, Mexico.
Universidad Insurgentes · MXInstituto Politécnico Nacional · MXMexican Institute of Petroleum · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present work, the preparation, characterisation, and efficiency of two different silica nanostructures as release vehicles of Cisplatin are reported. The 1-hexadeciltrimethyl-ammonium bromide templating agent was used to obtain mesoporous silica nanoparticles which were later loaded with Cisplatin. While sol-gel silica was very fast prepared using an excess of acetic acid during the hydrolysis-condensation reactions of tetraethylorthosilicate and at the same time the Cisplatin was added. Several physicochemical techniques including spectroscopies, electronic microscopy, X-ray diffraction, N

Indexed as

CisplatinDrug CarriersAnimalsBrain NeoplasmsCell Line, TumorNanoparticlesRatsSilicon DioxideCisplatinDrug CarriersSilicon Dioxide

Identifiers

PMID32338626
PMCPMC8676590
OpenAlexW2994938847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.