Evidence map›Paper›PMID 32338459›Full record

Trial reportPharmacology research & perspectives2020

Bioequivalence and pharmacodynamics of a generic dabigatran etexilate capsule in healthy Chinese subjects under fasting and fed conditions.

Xin Li, Lihua Liu, Bing Xu, Qian Xiang, Yuan Li, Ping Zhang, Yangyang Wang, Qiufen Xie, Yong Mao, Yimin Cui

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Pharmacology research & perspectives, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Frontiers in genetics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin LiDepartment of Pharmacy, The Third Hospital of Changsha, Changsha, The People's Republic of China.ORCID 0000-0002-8866-6848
Lihua LiuDepartment of Pharmacy, The Third Hospital of Changsha, Changsha, The People's Republic of China.
Bing XuDepartment of Pharmacy, The Third Hospital of Changsha, Changsha, The People's Republic of China.
Qian XiangDepartment of Pharmacy, Peking University First Hospital, Beijing, The People's Republic of China.
Yuan LiDepartment of Pharmacy, The Third Hospital of Changsha, Changsha, The People's Republic of China.
Ping ZhangDepartment of Pharmacy, The Third Hospital of Changsha, Changsha, The People's Republic of China.
Yangyang WangDepartment of Pharmacy, The Third Hospital of Changsha, Changsha, The People's Republic of China.
Qiufen XieDepartment of Pharmacy, Peking University First Hospital, Beijing, The People's Republic of China.
Yong MaoChengdu Brilliant Pharmaceutical Co. Ltd, Chengdu, The People's Republic of China.
Yimin CuiDepartment of Pharmacy, Peking University First Hospital, Beijing, The People's Republic of China.ORCID 0000-0002-4186-1005

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess bioequivalence of a generic dabigatran etexilate capsule in healthy Chinese subjects under fasting and fed conditions. This was an open-label, single-center, randomized four-period crossover study with a 7-day washout period. A single oral dose of 150 mg generic dabigatran etexilate capsule (test drug) or a commercial dabigatran etexilate capsule (Pradaxa

Indexed as

AdolescentAdultAntithrombinsAsian PeopleCapsulesCross-Over StudiesDabigatranDrugs, GenericFastingFemaleFood-Drug InteractionsHealthy VolunteersHumansMaleProthrombinTherapeutic EquivalencyAntithrombinsCapsulesDabigatranDrugs, GenericFactor IIaProthrombinbioequivalencefood effectgeneric dabigatran etexilatepharmacodynamicspharmacokinetics

Identifiers

PMID32338459
PMCPMC7184321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.