Evidence map›Paper›PMID 32338148›Full record

ArticleEpigenetics2020

Overexpression of human-derived

Zhenhua Li, Yuanwu Ma, Guishuan Wang, Hanshu Wang, Yubing Dai, Yu Zhu, Shitao Chen, Xiaoguo Zheng, Fei Sun

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Zhenhua LiInternational Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai, China.
Yuanwu MaKey Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC), Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences , Beijing, China.ORCID 0000-0002-1882-1777
Guishuan WangMedical School, Institute of Reproductive Medicine, Nantong University , Nantong, Jiangsu, China.
Hanshu WangInternational Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai, China.
Yubing DaiInternational Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai, China.
Yu ZhuInternational Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai, China.
Shitao ChenInternational Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai, China.ORCID 0000-0003-1006-5441
Xiaoguo ZhengInternational Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai, China.ORCID 0000-0003-0495-8964
Fei SunInternational Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai, China.
Shanghai Jiao Tong University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mammals, DNA methylation patterns are established by various types of DNA methyltransferases and can be stably passed on during cell division, thus creating a paradigm for epigenetic regulation that can mediate long-lasting changes in gene expression even when the initial triggering signal has disappeared. Although functional deficiency of

Indexed as

DNA MethylationEpigenesis, GeneticGenetic VariationAnimalsBrainDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3AHumansMaleRatsRats, Sprague-DawleyTestisTranscriptomeTransgenesDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanDNA methylationDNMT3Agene expressionintergenerational inheritancemRNA-seq

Identifiers

PMID32338148
PMCPMC7518692
OpenAlexW3018083741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.