Evidence map›Paper›PMID 32337977›Full record

ArticleACS applied materials & interfaces2020

Dual-Color Plasmonic Nanosensor for Radiation Dosimetry.

Yu Tao, Mingqiang Li, Xiangyu Liu, Kam W Leong, Jean Gautier, Shan Zha

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu TaoInstitute for Cancer Genetics, Columbia University, New York, New York 10032, United States.
Mingqiang LiDepartment of Biomedical Engineering, Columbia University, New York, New York 10027, United States.ORCID http://orcid.org/0000-0002-5178-4138
Xiangyu LiuInstitute for Cancer Genetics, Columbia University, New York, New York 10032, United States.
Kam W LeongDepartment of Biomedical Engineering, Columbia University, New York, New York 10027, United States.
Jean GautierInstitute for Cancer Genetics, Columbia University, New York, New York 10032, United States.ORCID http://orcid.org/0000-0002-6348-6023
Shan ZhaInstitute for Cancer Genetics, Columbia University, New York, New York 10032, United States.

Funding

The Role of CTIP in Lymphocyte Development and LymphomagenesisP01CA174653 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RABADAN, RAUL · 2014 to 2024
$17.6M
DNA Repair and Genomic Instability in Cancer Development and TherapyR35CA197606 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GAUTIER, JEAN · 2015 to 2021
$5.7M
The role of ATM in the suppression of lymphoid malignancyR01CA158073 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Shan Zha · 2011 to 2026
$5.7M
NCI NIH HHS P01 CA174653NCI NIH HHS R01 CA158073NCI NIH HHS R35 CA197606
6 · The paper itself

Abstract

Radiation dosimeters are critical for accurately assessing the levels of radiation exposure of tumor sites and surrounding tissues and for optimizing therapeutic interventions as well as for monitoring environmental exposure. To fill the need for a simple, user-friendly, and inexpensive dosimeter, we designed an innovative colorimetric nanosensor-based assay for detecting ionizing radiation. We show that hydroxyl radicals generated by ionizing radiation can be used to etch gold nanorods (AuNRs) and silver nanoprisms (AgNPRs), yielding reproducible color changes for radiation dose detection in the range of 50-2000 rad, broad enough to cover doses used in hyperfractionated, conventional, and hypofractionated radiotherapy. This range of doses detected by this assay correlates with radiation-induced DNA damage response in mammalian cells. Furthermore, this AuNR- and AgNPR-based sensing platform has been established in a paper format that can be readily adopted for a wide range of applications and translation.

Indexed as

Radiation, IonizingAnimalsColorColorimetryDNA DamageFibroblastsGoldMetal NanoparticlesMiceNanotubesPaperRadiometrySilverGoldSilvercolorimetric detectiondual-color nanosensorgold nanorodsradiation dosimetrysilver nanoprisms

Identifiers

PMID32337977
PMCPMC7346094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.