ArticleJournal of applied clinical medical physics2020
Dosimetric assessment of patient-specific breath-hold reproducibility on liver motion for SBRT planning.
Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 17 citations in OpenAlex.
- Implementation of surface-guided radiotherapy for motion management in liver SBRT: A scoping review and clinical workflow development.Technical innovations & patient support in radiation oncology · 2026Article
- A systematic review of tumour position reproducibility and stability in breath-hold for radiation therapy of the upper abdomen.Physics and imaging in radiation oncology · 2025Review
- Real-time 3D synthetic MRI based on kV imaging for motion monitoring of abdominal radiotherapy in a conventional LINAC.Physics in medicine and biology · 2025Article
- Clinical implementation and evaluation of stereotactic liver radiotherapy in inspiration breath-hold using nasal high-flow therapy and surface guidance.The British journal of radiology · 2024Article
- Analysis of respiratory-induced motion trajectories of individual liver segments in patients with hepatocellular carcinoma.Journal of applied clinical medical physics · 2024Article
- Online verification of breath-hold reproducibility using kV-triggered imaging for liver stereotactic body radiation therapy.Journal of applied clinical medical physics · 2023Article
- Selection of motion management in liver stereotactic body radiotherapy and its impact on treatment time.Physics and imaging in radiation oncology · 2023Article
- A review of surface guidance in extracranial stereotactic body radiotherapy (SBRT/SABR) for set-up and intra-fraction motion management.Technical innovations & patient support in radiation oncology · 2022Article
- The delivered dose assessment in pancreas SBRT with the target position determined using an in-house position monitoring system.Frontiers in oncology · 2022Article
- Novel Clinically Weight-Optimized Dynamic Conformal Arcs (WO-DCA) for Liver SBRT: A Comparison with Volumetric Modulated Arc Therapy (VMAT).Therapeutics and clinical risk management · 2021Article
- Impact on liver position under breath-hold by computed tomography contrast agents in stereotactic body radiotherapy of liver cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2021Article
- Evaluation of Residual Liver Motion Using Multiphase Computed Tomography in Stereotactic Body Radiotherapy: A Comparison of Three Motion Management Techniques.Journal of medical physicsArticle
- Interfractional Liver Positional Motion Under Exhaled Breath Holding Based on Cone Beam Computed Tomography.In vivo (Athens, Greece)Article
- Influence of intra- and interfraction motion on planning target volume margin in liver stereotactic body radiation therapy using breath hold.Advances in radiation oncologyArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the impact of breath-hold reproducibility on liver motion using a respiratory motion management device.
methodsForty-four patients with hepatic tumors, treated with SBRT with breath-hold, were randomly selected for this study. All patients underwent three consecutive computed tomography (CT) scans using active breath-hold coordinator (ABC) with three repeated single breath-hold during simulation. The three CT scans were labeled as ABC1-CT, ABC2-CT, and ABC3-CT. Displacements of centroids of the entire livers among the three ABC-CTs were measured as a surrogate for intrafractional motion. For each patient, two different treatment plans were prepared: (a) a clinical plan using a 5-mm expansion of an ITV that encompassed all three GTVs from each of the three ABC-CTs, and (b) a research plan using a 5-mm expansion of the GTV from only ABC1-CT to create PTV. The clinical plan acceptance criteria were that 95% of the PTV and 99% of the GTV received 100% of the prescription dose. Dosimetric endpoints were analyzed and compared for the two plans.
resultsAll shifts in the medial-lateral direction (range: -3.9 to 2.0 mm) were within 5 mm while 7% of shifts in the anterior-posterior direction (range: -10.5 to 16.7 mm) and 11% of shifts in the superior-inferior direction (range: -17.0 to 8.7 mm) exceeded 5 mm. Six patients (14%) had an intrafraction motion greater than 5 mm in any direction. For these six patients, if a plan was created based on a PTV from a single CT (ex. ABC1-CT), 5 of 12 GTVs captured from other ABC-CTs would fail to meet the clinical acceptance criteria due to poor breath-hold reproducibility.
conclusionsNon-negligible intrafractional motion occurs in patients with poor breath-hold reproducibility. To identify this subgroup of patients, acquiring three CTs with active breath-hold during simulation is a feasible practical method.
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