Evidence map›Paper›PMID 32337625›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Risk factors and the utility of three different kinds of prediction models for postoperative fatigue after gastrointestinal tumor surgery.

Xin-Yi Xu, Jin-Ling Lu, Qin Xu, Hong-Xia Hua, Le Xu, Li Chen

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Diagnostic predictive models for cancer-related fatigue: current evidence and future directions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin-Yi Xu *School of Nursing, Nanjing Medical University, Nanjing, China.
Jin-Ling Lu *School of Nursing, Nanjing Medical University, Nanjing, China.
Qin XuSchool of Nursing, Nanjing Medical University, Nanjing, China. 248629512@qq.com.
Hong-Xia HuaSchool of Nursing, Nanjing Medical University, Nanjing, China.
Le XuSchool of Health Policy & Management, Nanjing Medical University, Nanjing, China.
Li ChenDepartment of general surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Funding

Postgraduate Research & Practice Innovation Program of Jiangsu Province SJCX17_0393
6 · The paper itself

Abstract

backgroundPostoperative fatigue (POF) is a common complication after gastrointestinal tumor surgery, and it also brings negative effect on prognosis and life quality. However, there are no prediction models for POF, and studies of risk factors are not comprehensive. Therefore, the aim of this study is to investigate the risk factors and pick out the best prediction model for POF and to validate it.

methodsA prospective study was conducted for patients undergoing elective gastrointestinal tumor surgery. Physiological, psychological, and socioeconomic factors were collected. Logistic regression, back-propagation artificial neural networks (BP-ANNs), and classification and regression tree (CART) were constructed and compared.

resultsA total of 598 patients consisting of 463 derivation sample and 135 validation sample were included. The incidence of POF in derivation sample, validation sample, and total were 58.3%, 57.0%, and 58.7%, respectively. Logistic regression results showed age, higher degree of education, lower personal monthly income, advanced cancer, hypoproteinemia, preoperative anxiety or depression, and limited social support were risk factors for POF. Receiver operating characteristic curve (ROC) and performance indices were used to test three models. BP-ANN was the best by the comparison of models, and its strong predictive performance was also validated.

conclusionsMore attention should be paid on specific patients after gastrointestinal tumor surgery. BP-ANN is a powerful mathematical tool that could predict POF exactly. It may be used as a noninvasive screening tool to guide clinicians for early identification of high-risk patients and grading interventions.

Indexed as

AdultDigestive System Surgical ProceduresFatigueFemaleGastrointestinal NeoplasmsHumansIncidenceLogistic ModelsMaleMiddle AgedNeural Networks, ComputerPostoperative ComplicationsPostoperative PeriodPrognosisProspective StudiesRisk AssessmentBack-propagation artificial neural networksClassification and regression treeGastrointestinal neoplasmsLogistic regressionPostoperative fatigue

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.