Evidence map›Paper›PMID 32337372›Full record

ArticleNPJ digital medicine2020

Protected Health Information filter (Philter): accurately and securely de-identifying free-text clinical notes.

Beau Norgeot, Kathleen Muenzen, Thomas A Peterson, Xuancheng Fan, Benjamin S Glicksberg, Gundolf Schenk, Eugenia Rutenberg, Boris Oskotsky, Marina Sirota, Jinoos Yazdany and 4 more

Open access · goldAbstract read
In one paragraph

Article in NPJ digital medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 101 citations in OpenAlex.

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  7. Assessing genetic counseling efficiency with natural language processing.Journal of the American Medical Informatics Association : JAMIA · 2026
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  10. A Dataset of Psychiatric Hospital Notes with Temporal Information Annotations.LREC ... International Conference on Language Resources & Evaluation : [proceedings]. International Conference on Language Resources & Evaluation · 2026
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  12. Large language models accurately identify immunosuppression in intensive care unit patients.Journal of the American Medical Informatics Association : JAMIA · 2025
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  17. Review
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Beau Norgeot1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.
Kathleen Muenzen1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.ORCID 0000-0002-0840-614X
Thomas A Peterson1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.ORCID 0000-0002-2562-6574
Xuancheng Fan1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.
Benjamin S Glicksberg1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.ORCID 0000-0003-4515-8090
Gundolf Schenk1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.ORCID 0000-0003-1240-9949
Eugenia Rutenberg1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.
Boris Oskotsky1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.
Marina Sirota1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.
Jinoos Yazdany2Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA USA.
Gabriela Schmajuk2Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA USA.
Dana Ludwig1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.
Theodore Goldstein1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.
Atul J Butte1Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA USA.ORCID 0000-0002-7433-2740
University of California, San Francisco · USSan Francisco VA Medical Center · USUniversity of California System · US

Funding

RESOURCE-BASED CENTER FOR THE ADVANCEMENT OF PRECISION MEDICINE IN RHEUMATOLOGYP30AR070155 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mary C Nakamura · 2016 to 2026
$8.2M
Advancing Quality and Outcomes Measurement in RheumatologyK24AR074534 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jinoos Yazdany · 2019 to 2026
$1.5M
NIAMS NIH HHS K24 AR074534NIAMS NIH HHS P30 AR070155
6 · The paper itself

Abstract

There is a great and growing need to ascertain what exactly is the state of a patient, in terms of disease progression, actual care practices, pathology, adverse events, and much more, beyond the paucity of data available in structured medical record data. Ascertaining these harder-to-reach data elements is now critical for the accurate phenotyping of complex traits, detection of adverse outcomes, efficacy of off-label drug use, and longitudinal patient surveillance. Clinical notes often contain the most detailed and relevant digital information about individual patients, the nuances of their diseases, the treatment strategies selected by physicians, and the resulting outcomes. However, notes remain largely unused for research because they contain Protected Health Information (PHI), which is synonymous with individually identifying data. Previous clinical note de-identification approaches have been rigid and still too inaccurate to see any substantial real-world use, primarily because they have been trained with too small medical text corpora. To build a new de-identification tool, we created the largest manually annotated clinical note corpus for PHI and develop a customizable open-source de-identification software called Philter ("Protected Health Information filter"). Here we describe the design and evaluation of Philter, and show how it offers substantial real-world improvements over prior methods.

Indexed as

Health careMedical research

Identifiers

PMID32337372
PMCPMC7156708
OpenAlexW3017330637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.