ArticleBioMed research international2020
Reproductive Risk Factors Associated with Breast Cancer Molecular Subtypes among Young Women in Northern China.
Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Systematic Review and Meta-Analysis of Lifestyle and Reproductive Factors Associated with Risk of Breast Cancer in Asian Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Pooled it
- The unique risk factor profile of triple-negative breast cancer: a comprehensive meta-analysis.Journal of the National Cancer Institute · 2024Pooled it
- Association of reproductive risk factors and breast cancer molecular subtypes: a systematic review and meta-analysis.BMC cancer · 2023Pooled it
- Risk factors of breast cancer in women referring to the surgical clinic of northern Iran Hospitals over a ten-year period (2011-2021).Caspian journal of internal medicine · 2026Article
- Understanding Trends in Incidence and Management of Pregnancy-Associated Breast Cancer in a National Sample Using Claims Data.Journal of surgical oncology · 2025Article
- Immunohistochemical Evaluation of Perlecan (Heparan Sulphate Proteoglycan 2) Expression in Invasive Female Breast Carcinoma.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Breast Carcinoma Receptor Expression in a Caribbean Population.Surgery journal (New York, N.Y.) · 2022Article
- The Impact of Reproductive Factors on the Risk of Breast Cancer by ER/PR and HER2: A Multicenter Case-Control Study in Northern and Eastern China.The oncologist · 2022Article
- Knowledge, attitude, practice and factors that influence the awareness of college students with regards to breast cancer.World journal of clinical cases · 2022Article
- The distribution of reproductive risk factors disclosed the heterogeneity of receptor-defined breast cancer subtypes among Tanzanian women.BMC women's health · 2021Article
- Relationship of established risk factors with breast cancer subtypes.Cancer medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAccumulated evidence suggests that reproductive factors are related to different breast cancer subtypes, but most studies on these relationships are mainly focused on middle-aged and older patients, and it remains unclear how reproductive factors impact different subtypes of breast cancer in young women.
methodsWe assessed the relationships between fertility factors and luminal A, luminal B, human epidermal growth factor receptor 2 (HER2)-enriched, and triple-negative breast cancer (TNBC) subtypes in 3792 patients and 4182 controls aged 20-70 years. Data on the reproductive history of the study participants were acquired through face-to-face interviews and questionnaires. We conducted case-control comparisons among tumor subtypes based on estrogen receptor (ER), progesterone receptor (PR), and HER2 statuses using unconditional polychotomous multivariate logistic regression models to compute odds ratios (ORs) and 95% confidence intervals (CIs).
resultsParity was inversely related to both luminal A and luminal B subtypes in young women and older women (all
conclusionsOur results implied that parity exerted a strong protective effect against luminal A and luminal B subtype breast cancer in young Chinese women, and long-term breastfeeding obviously decreased the risk of luminal B and TNBC subtypes in this population.
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