Evidence map›Paper›PMID 32337255›Full record

ArticleBioMed research international2020

Dielectrophoresis-Based Method for Measuring the Multiangle Mechanical Properties of Biological Cells.

Botao Zhu, Wanting Li, Mingjie Zhu, Po-Lin Hsu, Lining Sun, Hao Yang

RetractedAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Botao ZhuRobotics and Microsystems Center, School of Mechanical and Electric Engineering, Soochow University, Suzhou, Jiangsu, China.
Wanting LiRobotics and Microsystems Center, School of Mechanical and Electric Engineering, Soochow University, Suzhou, Jiangsu, China.
Mingjie ZhuRobotics and Microsystems Center, School of Mechanical and Electric Engineering, Soochow University, Suzhou, Jiangsu, China.
Po-Lin HsuArtificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou, Jiangsu, China.
Lining SunRobotics and Microsystems Center, School of Mechanical and Electric Engineering, Soochow University, Suzhou, Jiangsu, China.
Hao YangRobotics and Microsystems Center, School of Mechanical and Electric Engineering, Soochow University, Suzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-4516-1321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanical properties of cells are closely related to their physiological functions and states. Analyzing and measuring these properties are beneficial to understanding cell mechanisms. However, most measurement methods only involve the unidirectional analysis of cellular mechanical properties and thus result in the incomplete measurement of these properties. In this study, a microfluidic platform was established, and an innovative microfluidic chip was designed to measure the multiangle cellular mechanical properties by using dielectrophoresis (DEP) force. Three unsymmetrical indium tin oxide (ITO) microelectrodes were designed and combined with the microfluidic chip, which were utilized to generate DEP force and stretch cell from different angles. A series of experiments was performed to measure and analyze the multiangle mechanical properties of red blood cells of mice. This work provided a new tool for the comprehensive and accurate measurement of multiangle cellular mechanical properties. The results may contribute to the exploration of the internal physiological structures of cells and the building of accurate cell models.

Indexed as

AnimalsElectrophoresisEquipment DesignLab-On-A-Chip DevicesMechanical PhenomenaMiceMicroelectrodesMicrofluidic Analytical TechniquesTin Compoundsindium tin oxideTin Compounds

Identifiers

PMID32337255
PMCPMC7165318

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.