Evidence map›Paper›PMID 32337222›Full record

ArticleBioMed research international2020

Human Epididymis Protein 4 Levels in Neonates with Respiratory Disorder.

Piotr Surmiak, Martyna Szymkowiak, Małgorzata Baumert

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Piotr SurmiakDepartment of Neonatology, Medical University of Silesia in Katowice, Faculty of Medical Sciences, Katowice 40-055, Poland.ORCID https://orcid.org/0000-0003-3662-634X
Martyna SzymkowiakDepartment of Neonatology, Medical University of Silesia in Katowice, Faculty of Medical Sciences, Katowice 40-055, Poland.ORCID https://orcid.org/0000-0002-4143-2489
Małgorzata BaumertDepartment of Neonatology, Medical University of Silesia in Katowice, Faculty of Medical Sciences, Katowice 40-055, Poland.ORCID https://orcid.org/0000-0003-4865-7274
Medical University of Silesia · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

resultsThere were no differences found in the HE4 levels determined for the mothers' blood samples and umbilical cord blood samples in all investigated groups. In comparison with healthy children, the elevated HE4 levels were observed in neonates with TTN. Significant positive correlation between HE4 and CRP as well as PCT levels was observed in all investigated neonates. The receiver operating characteristic (ROC) curve analysis demonstrated the cut-off value for the serum HE4 in the researched neonates at the level of 318.5 pmol/L, yielding the sensitivity of 73.9% and specificity of 66.7% for the early diagnosis of TTN.

conclusionsSerum HE4 could be considered as a candidate biomarker for the early diagnosis of pulmonary dysfunction in the newborns.

Indexed as

AdultBiomarkersC-Reactive ProteinFemaleFetal BloodHumansInfant, NewbornMaleProspective StudiesSensitivity and SpecificityTransient Tachypnea of the NewbornWAP Four-Disulfide Core Domain Protein 2BiomarkersC-Reactive ProteinWAP Four-Disulfide Core Domain Protein 2WFDC2 protein, human

Identifiers

PMID32337222
PMCPMC7154981
OpenAlexW3014800136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.