ArticleERJ open research2020
Prevalence and incidence of, and risk factors for chronic cough in the adult population: the Rotterdam Study.
Article in ERJ open research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 83 citations in OpenAlex.
- Camlipixant in Refractory Chronic Cough: A Phase 2b, Randomized, Placebo-controlled Trial (SOOTHE).American journal of respiratory and critical care medicine · 2025Trial
- The P2X3 receptor antagonist filapixant in patients with refractory chronic cough: a randomized controlled trial.Respiratory research · 2023Trial
- Validation of a visual analog scale for assessing cough severity in patients with chronic cough.Therapeutic advances in respiratory diseaseTrial
- Leicester Cough Questionnaire validation and clinically important thresholds for change in refractory or unexplained chronic cough.Therapeutic advances in respiratory diseaseTrial
- Prevalence and risk factors for refractory and untreated chronic cough in the Canadian Longitudinal Study of Aging.ERJ open research · 2026Article
- Susceptibility Patterns and Factors Associated with Multidrug Antibiotic Resistance Among Patients with Productive Cough in Southwestern Uganda.Infection and drug resistance · 2026Article
- Chronic cough and chronic pruritus in older adults: a population-based cross-sectional study.ERJ open research · 2025Article
- Genomics of chronic dry cough unravels neurological pathways.The European respiratory journal · 2025Article
- Systemic inflammation mediates the relationship between urinary cadmium and chronic cough risk: findings based on multiple statistical models.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Accuracy of COuGH RefluX Score as a Predictor of Gastroesophageal Reflux Disease (GERD) in Mexican Patients with Chronic Laryngopharyngeal Symptoms: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2025Article
- Knowledge, attitudes, and practices of asthma patients in Inner Mongolia regarding differentiation between allergic rhinitis accompanied asthma and cough.Frontiers in public health · 2025Article
- Prevalence and factors associated with respiratory symptoms in an urban population: findings from BOLD study in Karachi, Pakistan.Discover medicine · 2025Article
- Chronic Cough Patient Perspective: questionnaire validation and symptom impact.ERJ open research · 2025Article
- Prevalence of refractory and unexplained chronic cough in adults treated in cough centre.ERJ open research · 2024Article
- Characteristics of US Medicare Beneficiaries with Chronic Cough vs. Non-Chronic Cough: 2011-2018.Journal of clinical medicine · 2024Article
- Article
- Cerebellar ataxia, neuropathy and vestibular areflexia syndrome: a neurogenic cough prototype.ERJ open research · 2024Article
- Prevalence, clinical characteristics, and disease burden of chronic cough in Italy: a cross-sectional study.BMC pulmonary medicine · 2024Article
- Epidemiology and Healthcare Service Utilization among Adults with Chronic Cough.Journal of clinical medicine · 2024Article
- Prevalence and burden of chronic cough in France.ERJ open research · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic cough is a common complaint in the general population but there are no precise data on the incidence of, and prospectively examined risk factors for chronic cough in a population-based setting. Therefore, we investigated the period prevalence, incidence and risk factors for chronic cough in adult subjects. In a prospective population-based cohort study among subjects aged ≥45 years, data on chronic cough were collected on two separate occasions using a standardised questionnaire. Chronic cough was defined as daily coughing for at least 3 months duration during the preceding 2 years. Potential risk factors were gathered by interview, physical examination and several investigations. Of the 9824 participants in this study, 1073 (10.9%) subjects had chronic cough at baseline. The prevalence of chronic cough increased with age and peaked in the eighth decade. In subjects aged <70 years, chronic cough was more common in women. During an average follow-up of 6 years, 439 incident cases of chronic cough occurred with an overall incidence rate of 11.6 per 1000 person-years (95% CI 10.6-12.8). In current smokers, the incidence of chronic cough was higher in men. In the multivariable analysis, current smoking, gastro-oesophageal reflux disease (GORD), asthma and COPD were identified as risk factors for chronic cough. Chronic cough is common among adults and highly prevalent in the older population. Current smoking, GORD, asthma and COPD are independent risk factors for chronic cough. Individuals at risk of developing chronic cough may benefit from smoking cessation and control of the underlying disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.