Evidence map›Paper›PMID 32337199›Full record

ArticleWorld journal of clinical cases2020

Acute myeloid leukemia with t(11;19)(q23;p13.1) in a patient with a gastrointestinal stromal tumor undergoing imatinib therapy: A case report.

Hong Jun Kim, Sun Kyung Baek, Chi Hoon Maeng, Si-Young Kim, Tae Sung Park, Jae Joon Han

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hong Jun KimDepartment of Hematology and Medical Oncology, Kyung Hee University, Seoul 02447, South Korea.
Sun Kyung BaekDepartment of Hematology and Medical Oncology, Kyung Hee University, Seoul 02447, South Korea.
Chi Hoon MaengDepartment of Hematology and Medical Oncology, Kyung Hee University, Seoul 02447, South Korea.
Si-Young KimDepartment of Hematology and Medical Oncology, Kyung Hee University, Seoul 02447, South Korea.
Tae Sung ParkDepartment of Laboratory Medicine, Kyung Hee University, Seoul 02447, South Korea.
Jae Joon HanDepartment of Hematology and Medical Oncology, Kyung Hee University, Seoul 02447, South Korea. anemia@khu.ac.kr.
Kyung Hee University Medical Center · KRKyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute myeloid leukemia (AML) harboring 11q23 translocations is classified as therapy-related AML in patients who have undergone prior treatment with cytotoxic agents. There have been only a few reports of AML that subsequently developed during imatinib mesylate (IM) treatment for gastrointestinal stromal tumors (GISTs). CASE SUMMARY: A 63-year-old woman was diagnosed with a hepatic GIST recurrence in April 2012; she was administered IM 400 mg/d. In November 2015, she developed dyspnea with pancytopenia while IM treatment was continued for 42 mo. A chromosome study using a bone marrow sample showed a 46, XX karyotype with t(11;19)(q23;p13.1) in 22 of 26 analyzed metaphase cells. Fluorescence

conclusionPhysicians should consider the potential risks of developing hematologic malignancies, including therapy-related AML, in patients with GISTs receiving IM treatment.

Indexed as

Acute myeloid leukemiaCase reportGastrointestinal stromal tumorImatinibKMT2AMyelodysplastic syndrome

Identifiers

PMID32337199
PMCPMC7176619
OpenAlexW3014618506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.