Evidence map›Paper›PMID 32337175›Full record

ArticleAnesthesiology and pain medicine2020

Risk of Opioid Use Disorder from Exposure to Opioids in the Perioperative Period: A Systematic Review.

Khalid M Malik, Farnad Imani, Rena Beckerly, Rani Chovatiya

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anesthesiology and pain medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06177379 (Magnetic Resonance Neurography Analysis of Healthy Human Thoracic Dorsal Root Ganglion), which is not on this map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06177379 completednot on this mapstarted 2023, after this paper: background citation

Magnetic Resonance Neurography Analysis of Healthy Human Thoracic Dorsal Root Ganglion

TypeobservationalSponsorHuazhong University of Science and TechnologyRan2023 to 2023Enrolled90ConditionsDorsal Root GanglionArmshealthy volunteer
3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Article
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Khalid M MalikCollege of Medicine, University of Illinois, Chicago, USA.
Farnad ImaniPain Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-0814-0772
Rena BeckerlyDepartment of Anesthesiology, University of Illinois, Chicago, USA.
Rani ChovatiyaDepartment of Anesthesiology, University of Illinois, Chicago, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opioid use disorder, a major source of morbidity and mortality globally, is regularly linked to opioids given around the time of surgery. Perioperative period, however, is markedly heterogeneous, with the diverse providers using opioids distinctively, and the various drivers of opioid misuse at-play dissimilarly, throughout the perioperative period. The risk of opioid use disorder may, therefore, be different from opioids given at the various phases of perioperative care, and the ensuing recommendations for their use may also be dissimilar. Systematic search and analysis of the pertinent literature, following the accepted standards, showed an overall increased risk of misuse from the perioperative opioids. However, the analyzed studies had significant methodological limitations, and were constrained mainly to the out-patient phase of the perioperative period. Lacking any data, this risk, therefore, is unknown for intraoperative and postoperative recovery periods. Consequently, no firm recommendations can be extended to anesthesia providers generally managing these perioperative stages. Furthermore, with significant methodological limitations, the current recommendations for opioid use after surgery are also arbitrary. Thus, though proposals for perioperative opioid use are formulated in this article, substantive recommendations would require clear delineation of these risks, while avoiding the limitations noted in this review.

Indexed as

AddictionKeywords:OpioidPerioperative Care

Identifiers

PMID32337175
PMCPMC7158240

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.