Evidence map›Paper›PMID 32337075›Full record

ArticleNPJ vaccines2020

Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination.

David Pejoski, Casimir de Rham, Paola Martinez-Murillo, Francesco Santoro, Floriane Auderset, Donata Medaglini, Gianni Pozzi, Maria Vono, Paul-Henri Lambert, Angela Huttner and 7 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Microbiology spectrum · 2026
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  9. A recombinant VSV-vectored vaccine rapidly protects nonhuman primates against lethal Nipah virus disease.Proceedings of the National Academy of Sciences of the United States of America · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 18 institutions in 9 countries.

David Pejoski1Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0001-5010-0550
Casimir de Rham1Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Paola Martinez-Murillo1Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Francesco Santoro4Department of Medical Biotechnologies, University of Siena, Siena, Italy.ORCID 0000-0003-3052-3518
Floriane Auderset1Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Donata Medaglini4Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Gianni Pozzi4Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Maria Vono1Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Paul-Henri Lambert1Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Angela Huttner2World Health Organization Collaborating Centre for Vaccine Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Mariëlle C Haks6Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Tom H M Ottenhoff6Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Jean Villard1Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Claire-Anne Siegrist1Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
VEBCON Consortium
VSV-EBOVAC Consortium
VSV-EBOPLUS Consortium
University of Geneva · CHUniversity of Siena · ITUniversitätsklinikum Tübingen · DELeiden University Medical Center · NLWorld Health Organization · CHKenya Medical Research Institute · KEUniversity of Gothenburg · SECentre de Recherche Médicales de Lambaréné · GASpiez Laboratory · CHNewLink Genetics (United States) · USToscana Life Sciences · ITUniversität Hamburg · DECrozet BioPharma (United States) · USEmory Healthcare · USMerck & Co., Inc., Rahway, NJ, USA (United States) · USNational Institute for Biological Standards and Control · GBSt George's, University of London · GBUniversity of Oxford · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

The rVSV-ZEBOV Ebolavirus vaccine confers protection within days after immunization, suggesting the contribution of innate immune responses. We report modulation of rVSV-ZEBOV vaccinee blood CD56

Indexed as

Innate immunityLive attenuated vaccinesVaccines

Identifiers

PMID32337075
PMCPMC7156503
OpenAlexW3017225030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.