Evidence map›Paper›PMID 32337068›Full record

ArticleNPJ genomic medicine2020

19p loss is significantly enriched in older age neuroblastoma patients and correlates with poor prognosis.

Vito Alessandro Lasorsa, Flora Cimmino, Marzia Ognibene, Katia Mazzocco, Giovanni Erminio, Martina Morini, Massimo Conte, Achille Iolascon, Annalisa Pezzolo, Mario Capasso

Open access · goldAbstract read
In one paragraph

Article in NPJ genomic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. HGG advances · 2023
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  8. Neuroblastoma Patients' Outcome and Chromosomal Instability.International journal of molecular sciences · 2023
    Article
  9. Germline pathogenicJournal of medical genetics · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Vito Alessandro Lasorsa1Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Napoli, Italy.ORCID 0000-0002-9552-7192
Flora Cimmino1Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Napoli, Italy.
Marzia Ognibene3Laboratorio Cellule Staminali Post Natali e Terapie Cellulari, IRCCS Istituto Giannina Gaslini, Genova, Italy.ORCID 0000-0003-3698-9319
Katia Mazzocco4UOC Anatomia Patologica, IRCCS Istituto Giannina Gaslini, Genova, Italy.
Giovanni Erminio5Epidemiologia e Biostatistica IRCCS Istituto Giannina Gaslini, Genova, Italy.
Martina Morini6Laboratorio di Biologia Molecolare, IRCCS Istituto Giannina Gaslini, Genova, Italy.
Massimo Conte7UOC Oncologia, IRCCS Istituto Giannina Gaslini, Genova, Italy.
Achille Iolascon1Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Napoli, Italy.
Annalisa Pezzolo3Laboratorio Cellule Staminali Post Natali e Terapie Cellulari, IRCCS Istituto Giannina Gaslini, Genova, Italy.ORCID 0000-0001-6321-5701
Mario Capasso1Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Napoli, Italy.
Istituto Giannina Gaslini · ITCeinge Biotecnologie Avanzate (Italy) · ITSDN Istituto di Ricerca Diagnostica e Nucleare · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic aberrations of neuroblastoma occurring in late childhood and adolescence are still understudied. Publicly available DNA copy number profiles of 556 tumors (discovery set) and of 208 tumors obtained by array-CGH assay (validation set) were used to test if 19p loss is significantly over-represented in children and adolescents with neuroblastoma. The 19p loss occurrence was separately tested within different age groups in the discovery and validation set and the resulting

Indexed as

Cancer genomicsPrognostic markers

Identifiers

PMID32337068
PMCPMC7160145
OpenAlexW3016392955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.