Evidence map›Paper›PMID 32337039›Full record

ArticleMolecular and clinical oncology2020

Circulating tumor cells and breast cancer-specific mutations in primary breast cancer.

Michal Mego, Marian Karaba, Tatiana Sedlackova, Juraj Benca, Gabriela Repiska, Lucia Krasnicanova, Jan Macuch, Gabriela Sieberova, Silvia Jurisova, Daniel Pindak and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. PARP-1 Expression andCancers · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Michal MegoSecond Department of Medical Oncology, Faculty of Medicine, Comenius University, 833 10 Bratislava, Slovakia.
Marian KarabaNational Cancer Institute, 833 10 Bratislava, Slovakia.
Tatiana SedlackovaInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, 811 08 Bratislava, Slovakia.
Juraj BencaNational Cancer Institute, 833 10 Bratislava, Slovakia.
Gabriela RepiskaInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, 811 08 Bratislava, Slovakia.
Lucia KrasnicanovaInstitute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University, 811 08 Bratislava, Slovakia.
Jan MacuchNational Cancer Institute, 833 10 Bratislava, Slovakia.
Gabriela SieberovaNational Cancer Institute, 833 10 Bratislava, Slovakia.
Silvia JurisovaSecond Department of Medical Oncology, Faculty of Medicine, Comenius University, 833 10 Bratislava, Slovakia.
Daniel PindakNational Cancer Institute, 833 10 Bratislava, Slovakia.
Katarina KalavskaSecond Department of Medical Oncology, Faculty of Medicine, Comenius University, 833 10 Bratislava, Slovakia.
Jozef MardiakSecond Department of Medical Oncology, Faculty of Medicine, Comenius University, 833 10 Bratislava, Slovakia.
Gabriel MinarikDepartment of Molecular Biology, Faculty of Natural Sciences, Comenius University, Mlynska dolina, 842 15 Bratislava, Slovakia.
Comenius University Bratislava · SKNational Institute of Cardiovascular Diseases · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating tumor cells (CTCs) play a pivotal role in tumor dissemination and progression, and are considered to be a critical part of the metastatic cascade. The aim of the present research article was to examine breast cancer-specific mutations in primary breast cancer (PBC) using targeted resequencing. A total of 78 patients with PBC were enrolled into this translational study. Reverse transcription-quantitative PCR assay for the expression of epithelial markers (

Indexed as

BRCA1/2circulating tumor cellsepithelial-to-mesenchymal transitionprimary breast cancertargeted resequencing

Identifiers

PMID32337039
PMCPMC7179389
OpenAlexW3014948577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.