Evidence map›Paper›PMID 32336977›Full record

ArticleNutrition & metabolism2020

Physiologic requirement for iron in pregnant women, assessed using the stable isotope tracer technique.

Jie Cai, Tongxiang Ren, Jiaxi Lu, Jinghuan Wu, Deqian Mao, Weidong Li, Yu Zhang, Min Li, Jianhua Piao, Lichen Yang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nutrition & metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Jie Cai *1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Tongxiang Ren *3National Institute of Metrology, National Research Center for Certified Reference Material, No.18, Bei San Huan Dong Lu, Chaoyang District, Beijing, 10050 People's Republic of China.
Jiaxi Lu *1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Jinghuan Wu1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Deqian Mao1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Weidong Li1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Yu Zhang1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Min Li1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Jianhua Piao1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Lichen Yang1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Yuxia Ma4Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang, Hebei 050017 People's Republic of China.
Jun Wang3National Institute of Metrology, National Research Center for Certified Reference Material, No.18, Bei San Huan Dong Lu, Chaoyang District, Beijing, 10050 People's Republic of China.
Xiaoguang Yang1The Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese center for disease control and prevention, 29 Nan Wei Road, Xicheng District, Beijing, 100050 People's Republic of China.
Chinese Center For Disease Control and Prevention · CNNational Institute of Metrology · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnowledge of the physiologic requirement for iron, the core index for the formulation of a dietary reference intake (DRI), is of great importance for the health of a pregnant woman and her fetus, and can help a mother accurately plan her iron supplementation. However, direct measurements of the physiologic requirement for iron during pregnancy are still lacking.

methodEleven women of reproductive age from Hebei Province, China, who planned to become pregnant in the near future, were enrolled between January and March 2015 and included in the final analysis. Subjects participated in a 2-week metabolic trial in which they consumed 50 mg of the stable isotope

resultsThe mean physiologic requirement for iron in the 11 subjects, across their entire pregnancies, was 3.05 mg.d

conclusionWe preliminarily explored the physiologic requirement for iron in pregnant women. The data demonstrated that pregnant women needed about twice iron than non-pregnant women. This research may be helpful for the design of future studies and the modification of iron DRIs.

trial registrationChiCTR, ChiCTR-OCH-14004302. Registered 14 February 2014, http://www.chictr.org.cn/showproj.aspx?proj=5267.

Indexed as

IronPhysiologic requirementPregnant womenStable isotope tracer technique

Identifiers

PMID32336977
PMCPMC7175517
OpenAlexW3018546130

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.