Evidence map›Paper›PMID 32336234›Full record

ArticleHypertension (Dallas, Tex. : 1979)2020

Total Atherosclerosis Burden of Baroreceptor-Resident Arteries Independently Predicts Blood Pressure Dipping in Patients With Ischemic Stroke.

Qi Kong, Xin Ma, Chen Wang, Xiangying Du, Yi Ren, Yungao Wan

Registry-linked trialAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06604117 (A Prospective, Open-label Study Evaluating the Effects of Probucol Combined with Statins on Atherosclerotic Characteristics and Prognosis in Patients with Ischemic Stroke), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06604117 recruitingstarted 2024, after this paper: background citation

A Prospective, Open-label Study Evaluating the Effects of Probucol Combined with Statins on Atherosclerotic Characteristics and Prognosis in Patients with Ischemic Stroke

Ran2024Enrolled200Registered outcomes6Posted comparisons0ConditionsAtherosclerosis of Artery, Ischemic Stroke, Lipid Disorder, StatinArmsProbucol, Statin
Open the trial in the graph
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Clinic and ambulatory blood pressures, blood pressure phenotypes and mortality in patients with a previous stroke.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Observational
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qi KongFrom the Department of Neurology (Q.K., X.M., Y.R.), Xuanwu Hospital, Capital Medical University, Beijing, China.
Xin MaFrom the Department of Neurology (Q.K., X.M., Y.R.), Xuanwu Hospital, Capital Medical University, Beijing, China.
Chen WangDepartment of Radiology (C.W., X.D.), Xuanwu Hospital, Capital Medical University, Beijing, China.
Xiangying DuDepartment of Radiology (C.W., X.D.), Xuanwu Hospital, Capital Medical University, Beijing, China.
Yi RenFrom the Department of Neurology (Q.K., X.M., Y.R.), Xuanwu Hospital, Capital Medical University, Beijing, China.
Yungao WanDepartment of Cardiology (Y.W.), Xuanwu Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nighttime blood pressure (BP) generally dips by 10% to 20% of the daytime values, and abnormal BP dipping may affect vascular health independently of BP level. The regulation of BP dipping involves arterial baroreflex, whose receptors mainly reside in carotid sinuses and aortic arch. Atherosclerosis in these baroreceptor-resident arteries (BRAs) is frequent among patients with ischemic stroke (IS) and might impair their BP-regulating capacity. We aimed to examine associations between atherosclerosis of BRA and BP dipping in patients with IS. BP dipping ratio was measured by 24-hour ambulatory blood pressure monitoring on the sixth day after IS. With computed tomography angiography, atherosclerosis conditions in 10 segments of carotid sinuses and aortic arch were scored and summed as total atherosclerosis burden of BRA. Among the 245 patients with IS, 78.0% had atherosclerosis in BRA. The total AS burden of BRA was negatively correlated with systolic BP dipping ratio (

Indexed as

Aorta, ThoracicAtherosclerosisCarotid SinusHypotensionIschemic StrokeAgedBlood Pressure Monitoring, AmbulatoryComputed Tomography AngiographyCorrelation of DataFemaleHeart Disease Risk FactorsHumansMalePressoreceptorsSeverity of Illness Indexatherosclerosisbaroreceptorbaroreflexblood pressurecarotid sinusdippingstroke

Identifiers

PMID32336234
PMCPMC7682798

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.