Evidence map›Paper›PMID 32336233›Full record

Observational studyHypertension (Dallas, Tex. : 1979)2020

T2* Placental Magnetic Resonance Imaging in Preterm Preeclampsia: An Observational Cohort Study.

Alison E P Ho, Jana Hutter, Laurence H Jackson, Paul T Seed, Laura Mccabe, Mudher Al-Adnani, Andreas Marnerides, Simi George, Lisa Story, Joseph V Hajnal and 2 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 75 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Toward Clinical Implementation of Magnetic Resonance Imaging for Placental Function.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Preeclampsia and eclampsia: Enhanced detection and treatment for morbidity reduction.Best practice & research. Clinical anaesthesiology · 2024
    Review
  12. Review
  13. Observational
  14. Article
  15. Article
  16. Real-time fetal brain tracking for functional fetal MRI.Magnetic resonance in medicine · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Alison E P HoFrom the Department of Women and Children's Health, School of Life Course Sciences (A.E.P.H., P.S., L.S., L.C.C.), King's College London, United Kingdom.
Jana HutterCentre for the Developing Brain (J.H., L.H.J., L.M., J.V.H., M.A.R.), King's College London, United Kingdom.
Laurence H JacksonCentre for the Developing Brain (J.H., L.H.J., L.M., J.V.H., M.A.R.), King's College London, United Kingdom.
Paul T SeedFrom the Department of Women and Children's Health, School of Life Course Sciences (A.E.P.H., P.S., L.S., L.C.C.), King's College London, United Kingdom.
Laura MccabeCentre for the Developing Brain (J.H., L.H.J., L.M., J.V.H., M.A.R.), King's College London, United Kingdom.
Mudher Al-AdnaniDepartment of Cellular Pathology, Guy's and St Thomas' Hospital, London, United Kingdom (M.A.-A., A.M., S.G.).
Andreas MarneridesDepartment of Cellular Pathology, Guy's and St Thomas' Hospital, London, United Kingdom (M.A.-A., A.M., S.G.).
Simi GeorgeDepartment of Cellular Pathology, Guy's and St Thomas' Hospital, London, United Kingdom (M.A.-A., A.M., S.G.).
Lisa StoryFrom the Department of Women and Children's Health, School of Life Course Sciences (A.E.P.H., P.S., L.S., L.C.C.), King's College London, United Kingdom.
Joseph V HajnalCentre for the Developing Brain (J.H., L.H.J., L.M., J.V.H., M.A.R.), King's College London, United Kingdom.
Mary A Rutherford *Centre for the Developing Brain (J.H., L.H.J., L.M., J.V.H., M.A.R.), King's College London, United Kingdom.
Lucy C Chappell *From the Department of Women and Children's Health, School of Life Course Sciences (A.E.P.H., P.S., L.S., L.C.C.), King's College London, United Kingdom.
King's College London · GB

Funding

Structure and function of the placenta from implantation to delivery: a next generation MRI approachU01HD087202 · NICHD · KING'S COLLEGE LONDON · PI ALEXANDER, DANIEL, ALJABAR, PAUL · 2015 to 2015
$3.2M
Department of Health RP-2014-05-019NICHD NIH HHS U01 HD087202Wellcome Trust 201374Wellcome Trust WT 203148/Z/16/Z
6 · The paper itself

Abstract

Placental dysfunction underlies the cause of pregnancies complicated by preeclampsia. The use of placental magnetic resonance imaging to provide an insight into the pathophysiology of preeclampsia and thus assess its potential use to inform prognosis and clinical management was explored. In this prospective observational cohort study, 14 women with preterm preeclampsia and 48 gestation-matched controls using 3-Tesla magnetic resonance imaging at median of 31.6 weeks (interquartile range [IQR], 28.6-34.6) and 32.2 weeks (IQR, 28.6-33.8), respectively, were imaged. The acquired data included T2-weighted images and T2* maps of the placenta, the latter an indicative measure of placental oxygenation. Placentae in women with preeclampsia demonstrated advanced lobulation, varied lobule sizes, high granularity, and substantial areas of low-signal intensity on T2-weighted imaging, with reduced entire placental mean T2* values for gestational age (2 sample

Indexed as

PlacentaPlacental InsufficiencyPre-EclampsiaAdultCohort StudiesFemaleGestational AgeHumansMagnetic Resonance AngiographyOrgan SizeOxygen ConsumptionPlacenta Growth FactorPlacental Function TestsPregnancyPregnancy TrimestersReproducibility of ResultsPlacenta Growth Factormagnetic resonance imagingplacentapreeclampsiapregnancy

Identifiers

PMID32336233
PMCPMC7682790
OpenAlexW3020359021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.