Evidence map›Paper›PMID 32335819›Full record

ReviewHead and neck pathology2021

Aggressive Intraosseous Myofibroma of the Maxilla: Report of a Rare Case and Literature Review.

John Lennon Silva Cunha, Carla Isabelly Rodrigues-Fernandes, Ciro Dantas Soares, Celeste Sánchez-Romero, Pablo Agustin Vargas, Cleverson Luciano Trento, Bruno Augusto Benevenuto de Andrade, Sílvia Ferreira de Sousa, Ricardo Luiz Cavalcanti de Albuquerque-Júnior

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in Head and neck pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Myofibromas of the jawbones in pediatric patients. A clinicopathological study.Medicina oral, patologia oral y cirugia bucal · 2025
    Article
  3. Article
  4. Article
  5. Myofibroma with Atypical Features can Mimic Low-Grade Myofibroblastic Sarcoma: Two Paediatric Cases.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  6. Review
  7. A rare case of cervical myofibroma in an infant: A case report.International journal of surgery case reports · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

John Lennon Silva CunhaOral Pathology Section, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, SP, Brazil.
Carla Isabelly Rodrigues-FernandesOral Pathology Section, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, SP, Brazil.
Ciro Dantas SoaresOral Pathology Section, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, SP, Brazil.
Celeste Sánchez-RomeroOral Pathology Section, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, SP, Brazil.
Pablo Agustin VargasOral Pathology Section, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, SP, Brazil.
Cleverson Luciano TrentoDepartment of Dentistry, Federal University of Sergipe (UFS), Aracaju, SE, Brazil.
Bruno Augusto Benevenuto de AndradeDepartment of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
Sílvia Ferreira de SousaDepartment of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Ricardo Luiz Cavalcanti de Albuquerque-JúniorLaboratory of Morphology and Experimental Pathology, Institute of Technology and Research, Tiradentes University (UNIT), Avenida Murilo Dantas, 300, Aracaju, SE, 49032-490, Brazil. ricardo.patologia@uol.com.br.
Universidade Estadual de Campinas (UNICAMP) · BRInstituto de Tecnologia e Pesquisa · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal de Sergipe · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myofibroma (MF) is a benign mesenchymal myofibroblast-derived tumor, which occurs most frequently in children, and rarely affects the maxilla. We reported a case of an aggressive intraosseous lesion found in the maxilla of a 9-year-old female child. Intraorally, the swelling extended from tooth 12 to 16, causing displacement of teeth 13, 14, and 15. Computed tomography revealed a large osteolytic lesion causing thinning and cortical erosion. Microscopically, the lesion showed a proliferation of spindle-shaped cells, with elongated nuclei and eosinophilic cytoplasm, arranged in interlaced fascicles. The immunohistochemical analysis revealed cytoplasmic positivity for α-SMA and HHF-35, and negativity for desmin, laminin, S-100, β-catenin, and CD34. Ki-67 was positive in 8% of tumor cells. The diagnosis was MF. Herein, we describe an additional case of central MF arising in the maxilla, including clinical, imaging, microscopical, and immunohistochemical features, as well as a review of the literature.

Indexed as

ChildFemaleHumansMaxillary NeoplasmsMyofibromaJawsMaxillaMyofibromaPediatrics

Identifiers

PMID32335819
PMCPMC8010050
OpenAlexW3017532823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.