Evidence map›Paper›PMID 32335812›Full record

ArticleCytotechnology2020

Adipose-tissue derived porcine mesenchymal stem cells efficiently ameliorate CCl

Shourong Liu, Ruihong Guo, Xiaoli Hou, Yue Zhang, Xiawei Jiang, Tiantian Wang, Xiaoyu Wu, Keyang Xu, Xiaoping Pan, Liang Qiao

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cytotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Shourong LiuDepartment of Liver Diseases, Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310014, China. lsr85463990@126.com.
Ruihong GuoThe Fourth Clinical College, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Xiaoli HouCollege of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Yue ZhangCollege of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Xiawei JiangCollege of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Tiantian WangCollege of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Xiaoyu WuCollege of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Keyang XuThe Fourth Clinical College, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Xiaoping PanCollege of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China. panxiaoping001@126.com.
Liang QiaoStorr Liver Centre, Westmead Institute for Medical Research, The University of Sydney and Westmead Hospital, Westmead, NSW, 2145, Australia. liang.qiao@sydney.edu.au.
Zhejiang Chinese Medical University · CNWestmead Institute · AU

Funding

Hangzhou Health Science Foundation 2016Z06National Undergraduate Innovation Training Program 201710344027Natural Science Foundation of Zhejiang Province LY17H030013Zhejiang Health Science Foundation 2017KY114
6 · The paper itself

Abstract

Adipose tissue derived mesenchymal stem cells (ADMSCs) may be an attractive therapeutic source for acute liver injury because of their high accessibility and non-invasiveness. Here, we investigated the therapeutic potentials of porcine ADMSCs for acute liver failure (ALF). The morphology, differentiation potential, expression patterns of cell surface markers and liver-specific genes were compared between the ADMSCs derived from the pigs with or without ALF. For therapeutic studies, the expanded porcine ADMSCs from either ALF pig (ALF-ADMSCs) or healthy control pig (Nor-ADMSCs) of passage 3 were transplanted into CCl

Indexed as

Acute liver failureAdipose derived mesenchymal stem cellsCell transplantationHepatocyte-specific genes

Identifiers

PMID32335812
PMCPMC7225243
OpenAlexW3019282020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.