Evidence map›Paper›PMID 32335743›Full record

ArticleLasers in medical science2020

Identification of oral cancer in OCT images based on an optical attenuation model.

Zihan Yang, Jianwei Shang, Chenlu Liu, Jun Zhang, Yanmei Liang

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Article in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zihan YangInstitute of Modern Optics, Nankai University, 38 Tongyan Road, Tianjin, 300350, China.
Jianwei ShangDepartment of Oral Pathology, Tianjin Stomatological Hospital; Hospital of Stomatology, Nankai University, Tianjin, 300041, China.
Chenlu LiuDepartment of Oral Medicine, Tianjin Stomatological Hospital; Hospital of Stomatology, Nankai University, Tianjin, 300041, China.
Jun ZhangDepartment of Oral-Maxillofacial Surgery, Tianjin Stomatological Hospital; Hospital of Stomatology, Nankai University, Tianjin, 300041, China.
Yanmei LiangInstitute of Modern Optics, Nankai University, 38 Tongyan Road, Tianjin, 300350, China. ymliang@nankai.edu.cn.

Funding

Fundamental Research Funds for the Central Universities 63191203National Natural Science Foundation of China 11374167National Natural Science Foundation of China 61875092Science and Technology Support Program of Tianjin 17YFZCSY00740
6 · The paper itself

Abstract

Surgery is still the first choice to treat oral cancer, where it is important to detect surgical margins in order to reduce cancer recurrence and maintain oral-maxillofacial function simultaneously. As a non-invasive and in situ imaging technique, optical coherence tomography (OCT) can obtain images close to the resolution of histopathology, which makes it have great potential in intraoperative diagnosis. However, it is not enough to find surgical margins accurately just observing OCT images directly and qualitatively. The purpose of this study is to identify oral cancer in OCT images by investigating the quantitative difference of cancer and non-cancer tissue. Based on an available optical attenuation model and the axial confocal PSF of a home-made swept source OCT system, by using fresh ex vivo human oral tissues from 14 patients of oral squamous cell carcinoma (OSCC) as the samples, diagnosis with sensitivity (97.88%) and specificity (83.77%) was achieved at the attenuation threshold of 4.7 mm

Indexed as

Tomography, Optical CoherenceAdultAgedCarcinoma, Squamous CellColorDatabases as TopicFemaleHumansImaging, Three-DimensionalMaleMiddle AgedMouth NeoplasmsReproducibility of ResultsROC CurveOptical attenuation modelOptical coherence tomographyOral squamous cell carcinoma (OSCC)Quantitative analysis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.