Evidence map›Paper›PMID 32335544›Full record

ArticleAging2020

RNA-seq analysis of potential lncRNAs for age-related hearing loss in a mouse model.

Tong Zhao, Xiuzhen Liu, Zehua Sun, Jinjin Zhang, Xiaolin Zhang, Chaoyun Wang, Ruishuang Geng, Tihua Zheng, Bo Li, Qing Yin Zheng

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. NcRNA: key and potential in hearing loss.Frontiers in neuroscience · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Tong ZhaoHearing and Speech Rehabilitation Institute, Binzhou Medical University, Yantai, China.
Xiuzhen LiuClinical Medicine Laboratory, Binzhou Medical University Hospital, Binzhou, China.
Zehua SunHearing and Speech Rehabilitation Institute, Binzhou Medical University, Yantai, China.
Jinjin ZhangHearing and Speech Rehabilitation Institute, Binzhou Medical University, Yantai, China.
Xiaolin ZhangDepartment of Otolaryngology-Head and Neck Surgery, Binzhou Medical University Hospital, Binzhou, China.
Chaoyun WangHearing and Speech Rehabilitation Institute, Binzhou Medical University, Yantai, China.
Ruishuang GengHearing and Speech Rehabilitation Institute, Binzhou Medical University, Yantai, China.
Tihua ZhengHearing and Speech Rehabilitation Institute, Binzhou Medical University, Yantai, China.
Bo LiHearing and Speech Rehabilitation Institute, Binzhou Medical University, Yantai, China.
Qing Yin ZhengDepartment of Otolaryngology- Head and Neck Surgery, Case Western Reserve University, Cleveland, USA.
Binzhou Medical University · CNBinzhou University · CNCase Western Reserve University · US

Funding

Deciphering the Usher I protein interactome using a geneticapproachR01DC015111 · NIDCD · CASE WESTERN RESERVE UNIVERSITY · PI ZHENG, QING Y · 2016 to 2020
$1.8M
Deciphering the Usher I protein interactome using a genetic approachR01DC009246 · NIDCD · CASE WESTERN RESERVE UNIVERSITY · PI ZHENG, QING Y · 2009 to 2013
$1.6M
NIDCD NIH HHS R01 DC009246NIDCD NIH HHS R01 DC015111
6 · The paper itself

Abstract

Age-related hearing loss (AHL) is an important health problem in the elderly population. Its molecular mechanisms have not been fully elucidated. In this study, we analyzed the differential expression of lncRNAs and mRNAs in the cochleae of six-week-old and one-year-old C57BL/6J mice through RNA-seq analysis. We found 738 and 2033 differentially expressed lncRNAs and mRNAs, respectively, in these two groups (corrected

Indexed as

Gene Expression RegulationAnimalsDisease Models, AnimalGene OntologyGene Regulatory NetworksMiceMice, Inbred C57BLPresbycusisRNA, Long NoncodingRNA-SeqRNA, Long Noncodingage-related hearing losslncRNAmRNARNA-seq

Identifiers

PMID32335544
PMCPMC7202524
OpenAlexW3019268840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.