Evidence map›Paper›PMID 32335336›Full record

ReviewJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2020

SARS-CoV-2: Is it the newest spark in the TORCH?

Kathleen M Muldoon, Karen B Fowler, Megan H Pesch, Mark R Schleiss

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04432779 (Impact of SARS-CoV-2 Infection During Pregnancy on Newborns and Young Children), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04432779 terminatednot on this map

Impact of SARS-CoV-2 Infection During Pregnancy on Newborns and Young Children

TypeobservationalSponsorCentre Hospitalier Universitaire Saint PierreRan2020 to 2022Enrolled1,362ConditionsPregnancy, Covid-19Armsno intervention
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Maternal and perinatal outcomes in pregnant women infected by SARS-CoV-2: A meta-analysis.European journal of obstetrics, gynecology, and reproductive biology · 2021
    Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. COVID-19: Consequences on pregnant women and neonates.Health sciences review (Oxford, England) · 2022
    Review
  11. Review
  12. Article
  13. Article
  14. Impact of maternal nutrition in viral infections during pregnancy.Biochimica et biophysica acta. Molecular basis of disease · 2021
    Review
  15. Review
  16. Review
  17. A case report of newborn infant with severe COVID-19 in Mexico: Detection of SARS-CoV-2 in human breast milk and stool.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  18. Article
  19. COVID-19 - What does a paediatrician need to know?Paediatric respiratory reviews · 2020
    Review
  20. [SARS-CoV-2 and Perinatal Aspects].Zeitschrift fur Geburtshilfe und Neonatologie · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Kathleen M MuldoonDepartment of Anatomy, College of Graduate Studies and Arizona College of Osteopathic Medicine, Midwestern University, Glendale, AZ, 85308, USA; National CMV Foundation, Tampa, FL, 33679, USA.
Karen B FowlerDepartment of Pediatrics, University of Alabama at Birmingham Medical School, Pediatric Division of Infectious Diseases, Birmingham, AL, 35233, USA; National CMV Foundation, Tampa, FL, 33679, USA.
Megan H PeschDepartment of Pediatrics, University of Michigan Medical School, Division of Developmental and Behavioral Pediatrics, Ann Arbor, MI, 48109, USA; National CMV Foundation, Tampa, FL, 33679, USA.
Mark R SchleissDivision of Pediatric Infectious Diseases and Immunology, University of Minnesota Medical School, Department of Pediatrics, Minneapolis, MN, 55455, USA; National CMV Foundation, Tampa, FL, 33679, USA. Electronic address: schleiss@umn.edu.
Midwestern University · USUniversity of Alabama at Birmingham · USUniversity of Michigan · USUniversity of Minnesota Medical Center · US

Funding

Optimizing Immunity and Maternal Host Defense Against Congenital Cytomegalovirus InfectionR01HD098866 · NICHD · UNIVERSITY OF MINNESOTA · PI Craig John Bierle, Michael A McVoy · 2019 to 2026
$3.9M
Optimized Vaccines Against Congenital Infection and Maternal Reinfection with CMVR01HD079918 · NICHD · UNIVERSITY OF MINNESOTA · PI SCHLEISS, MARK R. · 2015 to 2019
$1.6M
NICHD NIH HHS R01 HD079918NICHD NIH HHS R01 HD098866
6 · The paper itself

Abstract

Amid the rapidly evolving global coronavirus disease 2019 (COVID-19) pandemic that has already had profound effects on public health and medical infrastructure globally, many questions remain about its impact on child health. The unique needs of neonates and children, and their role in the spread of the virus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) should be included in preparedness and response plans. Fetuses and newborn infants may be uniquely vulnerable to the damaging consequences of congenitally- or perinatally-acquired SARS-CoV-2 infection, but data are limited about outcomes of COVID-19 disease during pregnancy. Therefore, information on illnesses associated with other highly pathogenic coronaviruses (i.e., severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome [MERS]), as well as comparisons to common congenital infections, such as cytomegalovirus (CMV), are warranted. Research regarding the potential routes of acquisition of SARS-CoV-2 infection in the prenatal and perinatal setting is of a high public health priority. Vaccines targeting women of reproductive age, and in particular pregnant patients, should be evaluated in clinical trials and should include the endpoints of neonatal infection and disease.

Indexed as

AnimalsBetacoronavirusCoronavirus InfectionsCOVID-19COVID-19 VaccinesDisease Models, AnimalFemaleHumansInfant HealthInfant, NewbornPandemicsPneumonia, ViralPregnancyPregnancy Complications, InfectiousSARS-CoV-2Severe Acute Respiratory SyndromeCOVID-19 VaccinesViral VaccinesCongenital infectionCOVID-19SARS-CoV-2SARS-CoV-2 vaccinesTORCH infection

Identifiers

PMID32335336
PMCPMC7195345
OpenAlexW3016311027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.