ArticleNeuroImage2020
Strong diffusion gradients allow the separation of intra- and extra-axonal gradient-echo signals in the human brain.
Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Feasibility of strong diffusion encoding and fast readout using a plug-and-play head gradient insert at 7 T.Magnetic resonance in medicine · 2025Article
- In vivo cortical microstructure mapping using high-gradient diffusion MRI accounting for intercompartmental water exchange effects.NeuroImage · 2025Article
- Predicting Mesoscopic Larmor Frequency Shifts in White Matter With Diffusion MRI-A Monte Carlo Study in Axonal Phantoms.NMR in biomedicine · 2025Article
- The impact of head orientation with respect to BImaging neuroscience (Cambridge, Mass.) · 2023Article
- Tensor denoising of multidimensional MRI data.Magnetic resonance in medicine · 2023Article
- Larmor frequency shift from magnetized cylinders with arbitrary orientation distribution.NMR in biomedicine · 2023Article
- Estimating axial diffusivity in the NODDI model.NeuroImage · 2022Article
- Mutation-related magnetization-transfer, not axon density, drives white matter differences in premanifest Huntington disease: Evidence from in vivo ultra-strong gradient MRI.Human brain mapping · 2022Article
- Mapping the human connectome using diffusion MRI at 300 mT/m gradient strength: Methodological advances and scientific impact.NeuroImage · 2022Review
- Physiological effects of human body imaging with 300 mT/m gradients.Magnetic resonance in medicine · 2022Article
- What's new and what's next in diffusion MRI preprocessing.NeuroImage · 2022Review
- Combined diffusion-relaxometry microstructure imaging: Current status and future prospects.Magnetic resonance in medicine · 2021Review
- Quantifying myelin in crossing fibers using diffusion-prepared phase imaging: Theory and simulations.Magnetic resonance in medicine · 2021Article
- Measuring compartmental TNeuroImage · 2021Article
- Fiber ball white matter modeling in focal epilepsy.Human brain mapping · 2021Article
- The present and the future of microstructure MRI: From a paradigm shift to normal science.Journal of neuroscience methods · 2021Review
- Multi-compartment analysis of the complex gradient-echo signal quantifies myelin breakdown in premanifest Huntington's disease.NeuroImage. Clinical · 2021Article
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5 authors.
Funding
Abstract
The quantification of brain white matter properties is a key area of application of Magnetic Resonance Imaging (MRI), with much effort focused on using MR techniques to quantify tissue microstructure. While diffusion MRI probes white matter (WM) microstructure by characterising the sensitivity of Brownian motion of water molecules to anisotropic structures, susceptibility-based techniques probe the tissue microstructure by observing the effect of interaction between the tissue and the magnetic field. Here, we unify these two complementary approaches by combining ultra-strong (300mT/m) gradients with a novel Diffusion-Filtered Asymmetric Spin Echo (D-FASE) technique. Using D-FASE we can separately assess the evolution of the intra- and extra-axonal signals under the action of susceptibility effects, revealing differences in the behaviour in different fibre tracts. We observed that the effective relaxation rate of the ASE signal in the corpus callosum decreases with increasing b-value in all subjects (from 17.1±0.7s
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