Evidence map›Paper›PMID 32335067›Full record

GuidelineChest2020

Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic: CHEST Expert Panel Report.

Peter J Mazzone, Michael K Gould, Douglas A Arenberg, Alexander C Chen, Humberto K Choi, Frank C Detterbeck, Farhood Farjah, Kwun M Fong, Jonathan M Iaccarino, Samuel M Janes and 14 more

Open access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Chest, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

  1. Guideline
  2. Impacts of a Public Health Emergency on Cancer Testing Rates, Follow-up, and Cancer Diagnosis: An Evaluation of the COVID-19 Pandemic.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Observational
  16. Article
  17. Detection of subsolid nodules on chest CT scans during the COVID-19 pandemic.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
    Article
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 4 countries.

Peter J MazzoneRespiratory Institute, Cleveland Clinic, Cleveland, OH. Electronic address: mazzonp@ccf.org.
Michael K GouldDepartment of Research and Evaluation, Kaiser Permanente Research, Pasadena, CA.
Douglas A ArenbergDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI.
Alexander C ChenDivision of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO.
Humberto K ChoiDepartment of Medicine, Cleveland Clinic, Cleveland, OH.
Frank C DetterbeckSection of Thoracic Surgery, Department of Surgery, Yale University, New Haven, CT.
Farhood FarjahDepartment of Surgery, University of Washington, Seattle, WA.
Kwun M FongDepartment of Thoracic Medicine, The Prince Charles Hospital, Chermside, Australia.
Jonathan M IaccarinoThe Pulmonary Center, Boston University Medical Campus, Boston, MA.
Samuel M JanesLungs for Living Research Centre, University College London, London, England.
Jeffrey P KanneDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Ella A KazerooniDepartment of Radiology, University of Michigan, Ann Arbor, MI.
Heber MacMahonDepartment of Radiology, University of Chicago, Chicago, IL.
David P NaidichDepartment of Radiology, New York University-Langone Medical Center, New York, NY.
Charles A PowellDivision of Pulmonary, Critical Care, and Sleep Medicine, Icahn School of Medicine at Mt. Sinai, New York, NY.
Suhail RaoofDivision of Pulmonary, Critical Care, and Sleep Medicine, Lenox Hill Hospital, New York, NY.
M Patricia RiveraDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of North Carolina, Chapel Hill, NC.
Nichole T TannerDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Health Equity and Rural Outreach Innovation Center, Ralph H. Johnson Veterans Affairs Hospital, Charleston, SC.
Lynn K TanoueDepartment of Internal Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT.
Alain TremblayDivision of Respiratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Anil VachaniPulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, PA.
Charles S WhiteDepartment of Radiology, School of Medicine, University of Maryland, Baltimore, MD.
Renda Soylemez WienerThe Pulmonary Center, Boston University School of Medicine, Boston, MA; Center for Healthcare Organization & Implementation Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA.
Gerard A SilvestriDivision of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC.
Cleveland Clinic · USUniversity of Michigan–Ann Arbor · USYale University · USBoston Medical Center · USEdith Nourse Rogers Memorial Veterans Hospital · USIcahn School of Medicine at Mount Sinai · USKaiser Permanente · USLenox Hill Hospital · USMedical University of South Carolina · USNYU Langone Health · USPrince Charles Hospital · AURalph H. Johnson VA Medical Center · USUniversity College London · GBUniversity of Calgary · CAUniversity of Chicago · USUniversity of Maryland, Baltimore · USUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · USUniversity of Washington · USUniversity of Wisconsin–Madison · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Center for Research to Optimize Precision Lung Cancer Screening in Diverse PopulationsUM1CA221939 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI RITZWOLLER, DEBRA P, VACHANI, ANIL · 2018 to 2023
$15.3M
Cancer Research UK 28706NCATS NIH HHS UL1 TR001863NCI NIH HHS UM1 CA221939
6 · The paper itself

Abstract

backgroundThe risks from potential exposure to coronavirus disease 2019 (COVID-19), and resource reallocation that has occurred to combat the pandemic, have altered the balance of benefits and harms that informed current (pre-COVID-19) guideline recommendations for lung cancer screening and lung nodule evaluation. Consensus statements were developed to guide clinicians managing lung cancer screening programs and patients with lung nodules during the COVID-19 pandemic.

methodsAn expert panel of 24 members, including pulmonologists (n = 17), thoracic radiologists (n = 5), and thoracic surgeons (n = 2), was formed. The panel was provided with an overview of current evidence, summarized by recent guidelines related to lung cancer screening and lung nodule evaluation. The panel was convened by video teleconference to discuss and then vote on statements related to 12 common clinical scenarios. A predefined threshold of 70% of panel members voting agree or strongly agree was used to determine if there was a consensus for each statement. Items that may influence decisions were listed as notes to be considered for each scenario.

resultsTwelve statements related to baseline and annual lung cancer screening (n = 2), surveillance of a previously detected lung nodule (n = 5), evaluation of intermediate and high-risk lung nodules (n = 4), and management of clinical stage I non-small cell lung cancer (n = 1) were developed and modified. All 12 statements were confirmed as consensus statements according to the voting results. The consensus statements provide guidance about situations in which it was believed to be appropriate to delay screening, defer surveillance imaging of lung nodules, and minimize nonurgent interventions during the evaluation of lung nodules and stage I non-small cell lung cancer.

conclusionsThere was consensus that during the COVID-19 pandemic, it is appropriate to defer enrollment in lung cancer screening and modify the evaluation of lung nodules due to the added risks from potential exposure and the need for resource reallocation. There are multiple local, regional, and patient-related factors that should be considered when applying these statements to individual patient care.

Indexed as

Coronavirus InfectionsLung NeoplasmsPandemicsPneumonia, ViralBetacoronavirusCarcinoma, Non-Small-Cell LungConsensusCOVID-19Early Detection of CancerHumansMultiple Pulmonary NodulesNeoplasm StagingRadiography, ThoracicResource AllocationRisk AssessmentSARS-CoV-2consensus statementCOVID-19lung cancer screeninglung nodule

Identifiers

PMID32335067
PMCPMC7177089
OpenAlexW3020374319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.