Evidence map›Paper›PMID 32334596›Full record

ArticleBMC urology2020

Case series of glans injuries during voluntary medical male circumcision for HIV prevention - eastern and southern Africa, 2015-2018.

Todd J Lucas, Carlos Toledo, Stephanie M Davis, D Heather Watts, Joseph S Cavanaugh, Valerian Kiggundu, Anne G Thomas, Elijah Odoyo-June, Collen Bonnecwe, Tintswalo Hilda Maringa and 20 more

Open access · goldAbstract read
In one paragraph

Article in BMC urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Preventing HIV Among Adolescent Boys and Young Men Through PEPFAR-Supported Voluntary Medical Male Circumcision in 15 Sub-Saharan African Countries, 2018-2021.AIDS education and prevention : official publication of the International Society for AIDS Education · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Iatrogenic partial glanular amputation: A rare complication of circumcision.Indian journal of urology : IJU : journal of the Urological Society of India
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 17 institutions in 10 countries.

Todd J LucasEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA. tlucas@cdc.gov.
Carlos ToledoDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Stephanie M DavisDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Atlanta, GA, USA.
D Heather WattsU.S. Office of the Global HIV/AIDS Coordinator, Washington, D.C, USA.
Joseph S CavanaughU.S. Office of the Global HIV/AIDS Coordinator, Washington, D.C, USA.
Valerian KiggunduOffice of HIV/AIDS, U.S. Agency for International Development, Washington, D.C, USA.
Anne G ThomasDefense Health Agency, Department of Defense, San Diego, CA, USA.
Elijah Odoyo-JuneDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Nairobi, Kenya.
Collen BonnecweNational Department of Health, Pretoria, South Africa.
Tintswalo Hilda MaringaDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Pretoria, South Africa.
Enilda MartinU.S. Agency for International Development, Pretoria, South Africa.
Ambrose Wanyonyi JumaNational AIDS and STI Control Program, Ministry of Health, Nairobi, Kenya.
Sinokuthemba XabaMinistry of Health and Child Care, Harare, Zimbabwe.
Shirish BalachandraDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Harare, Zimbabwe.
Jotamo ComeMinistry of Health, Maputo, Mozambique.
Marcos CandaDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Maputo, Mozambique.
Rose NyirendaMinistry of Health, Lilongwe, Malawi.
Wezi MsungamaDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Lilongwe, Malawi.
James OdekU.S. Agency for International Development, Lilongwe, Malawi.
Gissenge J I LijaNational AIDS Control Program, Ministry of Health, Community Development, Gender, Elderly and Children, Dar es Salaam, Tanzania.
Erick MlangaU.S. Agency for International Development, Dar es Salaam, Tanzania.
James Exnobert ZuluMinistry of Health, Lusaka, Zambia.
Heidi O'BraU.S. Agency for International Development, Lusaka, Zambia.
Omega ChituwoDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Lusaka, Zambia.
Mekondjo AupokoloMinistry of Health and Social Services, Windhoek, Namibia.
Denis A MaliU.S. Agency for International Development, Windhoek, Namibia.
Brigitte ZemburukaDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Windhoek, Namibia.
Kananga Dany MalabaDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Gaborone, Botswana.
Onkemetse Conrad NtsuapeMinistry of Health and Wellness, Gaborone, Botswana.
Jonas Z HinesDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Centers for Disease Control and Prevention · USAIDS United · USAfrican Institute for Development Policy · MWCenters for Disease Control and Prevention · KECentre for Infectious Disease Research in Zambia · ZMDefense Health Agency · USDepartment of Health · ZAMinistry of Health · ZMMinistry of Health · KEMinistry of Health · MWMinistry of Health · MZMinistry of Health · BWMinistry of Health and Child Welfare · ZWMinistry of Health and Social Services · NAMinistry of Health, Community Development, Gender, Elderly and Children · TZPractical Action · ZWUnited States Agency for International Development · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMale circumcision confers partial protection against heterosexual HIV acquisition among men. The President's Emergency Plan for AIDS Relief (PEPFAR) has supported > 18,900,000 voluntary medical male circumcisions (VMMC). Glans injuries (GIs) are rare but devastating adverse events (AEs) that can occur during circumcision. To address this issue, PEPFAR has supported multiple interventions in the areas of surveillance, policy, education, training, supply chain, and AE management.

methodsSince 2015, PEPFAR has conducted surveillance of GIs including rapid investigation by the in-country PEPFAR team. This information is collected on standardized forms, which were reviewed for this analysis.

resultsThirty-six GIs were reported from 2015 to 2018; all patients were < 15 years old (~ 0·7 per 100,000 VMMCs in this age group) with a decreasing annual rate (2015: 0.7 per 100,000 VMMCs; 2018: 0.4 per 100,000 VMMC; p = 0.02). Most (64%) GIs were partial or complete amputations. All amputations among 10-14 year-olds occurred using the forceps-guided (FG) method, as opposed to the dorsal-slit (DS) method, and three GIs among infants occurred using a Mogen clamp. Of 19 attempted amputation repairs, reattached tissue was viable in four (21%) in the short term. In some cases, inadequate DS method training and being overworked, were found.

conclusionFollowing numerous interventions by PEPFAR and other stakeholders, GIs are decreasing; however, they have not been eliminated and remain a challenge for the VMMC program. Preventing further cases of complete and partial amputation will likely require additional interventions that prevent use of the FG method in young patients and the Mogen clamp in infants. Improving management of GIs is critical to optimizing outcomes.

Indexed as

AdolescentAfrica, EasternAfrica, SouthernChildChild, PreschoolCircumcision, MaleHIV InfectionsHumansInfantIntraoperative ComplicationsMalePenisAmputationHIVIntraoperative complicationsMale circumcision

Identifiers

PMID32334596
PMCPMC7183662
OpenAlexW3019321736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.