Evidence map›Paper›PMID 32334582›Full record

ArticleJournal of nanobiotechnology2020

Growth and elongation of axons through mechanical tension mediated by fluorescent-magnetic bifunctional Fe

Yang Wang, Binxi Li, Hao Xu, Shulin Du, Ting Liu, Jingyan Ren, Jiayi Zhang, Hao Zhang, Yi Liu, Laijin Lu

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Nuclear destabilisation - a possible genesis of cancer?Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  3. Review
  4. Review
  5. Study on Recovery Strategy of Hearing Loss & SGN Regeneration Under Physical Regulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Manipulation of Axonal Outgrowth via Exogenous Low Forces.International journal of molecular sciences · 2020
    Review
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yang WangDepartment of Hand Surgery, The First Hospital of Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Binxi LiState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, 130012, Jilin, People's Republic of China.
Hao XuInstitute of Translational Medicine, The First Hospital of Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Shulin DuState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, 130012, Jilin, People's Republic of China.
Ting LiuDepartments of Geriatrics, The First Hospital of Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Jingyan RenDepartment of Hand Surgery, The First Hospital of Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Jiayi ZhangDepartment of Hand Surgery, The First Hospital of Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Hao ZhangState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, 130012, Jilin, People's Republic of China.
Yi LiuState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, 130012, Jilin, People's Republic of China. yiliuchem@jlu.edu.cn.
Laijin LuDepartment of Hand Surgery, The First Hospital of Jilin University, Changchun, 130021, Jilin, People's Republic of China. lulaijin@hotmail.com.ORCID http://orcid.org/0000-0003-4244-7022
Jilin University · CN

Funding

Major Research Plan 81771329Young Scientists Fund 21875086
6 · The paper itself

Abstract

backgroundThe primary strategy to repair peripheral nerve injuries is to bridge the lesions by promoting axon regeneration. Thus, the ability to direct and manipulate neuronal cell axon regeneration has been one of the top priorities in the field of neuroscience. A recent innovative approach for remotely guiding neuronal regeneration is to incorporate magnetic nanoparticles (MNPs) into cells and transfer the resulting MNP-loaded cells into a magnetically sensitive environment to respond to an external magnetic field. To realize this intention, the synthesis and preparation of ideal MNPs is an important challenge to overcome.

resultsIn this study, we designed and prepared novel fluorescent-magnetic bifunctional Fe

conclusionsOur work demonstrates that FMSPs can be used as a novel stimulator to promote noninvasive neural regeneration through cell magnetic actuation.

Indexed as

AnimalsAxonsCadherinsCell SurvivalExocytosisFerrosoferric OxideGene Expression RegulationIndolesMagnetite NanoparticlesMiceMicroscopy, ConfocalMicroscopy, Electron, TransmissionNerve RegenerationOleic AcidPC12 CellsPolymersCadherinsFerrosoferric OxideIndolesMagnetite NanoparticlesOleic Acidosteoblast cadherinpolydopaminePolymersProtein Phosphatase 1rhodamine 6GRhodaminesAxon regenerationFe3O4 superparticlesGene expression profileMagnetic actuationMagnetic fieldMagnetic nanoparticlesMechanical forces

Identifiers

PMID32334582
PMCPMC7183675
OpenAlexW3020813493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.