ArticleBMC pregnancy and childbirth2020
Pregnancies after vaginal radical trachelectomy (RT) in patients with early invasive uterine cervical cancer: results from a single institute.
Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Fertility-Sparing Management of HPV-Associated FIGO IB1 Mucinous Cervical Adenocarcinoma With Signet-Ring Cell Features: A Case Report.Case reports in obstetrics and gynecology · 2026Article
- Efficacy of transabdominal cerclage by open laparotomy relative to existing risk factors.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Microbiological investigation of pregnancies following vaginal radical trachelectomy using 16S rRNA sequencing of FFPE placental specimens.FEBS open bio · 2024Article
- Article
- Surgical Treatment for Early Cervical Cancer in the HPV Era: State of the Art.Healthcare (Basel, Switzerland) · 2023Review
- Reproductive and Obstetric Outcomes after Fertility-Sparing Treatments for Cervical Cancer: Current Approach and Future Directions.Journal of clinical medicine · 2023Review
- Does radical trachelectomy (RT) during pregnancy have higher obstetrical and oncological risks than RT before pregnancy?Archives of gynecology and obstetrics · 2022Article
- Fetal biometric and Doppler measurements following abdominal radical trachelectomy in the second trimester of the pregnancy.BMC pregnancy and childbirth · 2022Article
- Early Cervical Lesions Affecting Ovarian Reserve and Reproductive Outcomes of Females in Assisted Reproductive Cycles.Frontiers in oncology · 2022Article
- Review
- Effect of Low-Frequency Electric Pulse Technique Combined with Carboprost Methylate Suppositories on Recovery of Gastrointestinal Function and Postoperative Complications of Patients with Scarred Uterus Undergoing Secondary Cesarean Section.Journal of healthcare engineering · 2021Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRadical tracheletomy (RT) with pelvic lymphadenectomy has become an option for young patients with early invasive uterine cervical cancer who desire to maintain their fertility. However, this operative method entails a high risk for the following pregnancy due to its radicality.
methodsWe have performed vaginal RT for 71 patients and have experienced 28 pregnancies in 21 patients. They were followed up carefully according to the follow-up methods we reported previously. Their pregnancy courses and prognoses after the pregnancy were retrospectively reviewed.
resultsAll the vaginal RTs were performed safely without serious complications, including 6 patients who underwent the operation during pregnancy. The median time to be pregnant after RT was 29.5 months. 13 patients (46%) became pregnant without artificial insemination by husband or assisted reproductive technology. Cesarean section was performed for all of them. The median time of pregnancy was 34 weeks, and emergent cesarean section was performed for 7 pregnancies (25%). The median birth weight was 2156 g. Four patients had trouble with cervical cerclage, and they suffered from sudden premature preterm rupture of the membrane (pPROM) during the second trimester of pregnancy. We underwent transabdominal cerclage (TAC) for all of them and careful management for the prevention of uterine infection was performed. One patient had a recurrence of cancer during pregnancy.
conclusionsBoth the obstetrical prognosis and oncological prognosis after vaginal RT have become favorable for pregnant patients after vaginal RT.
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