Evidence map›Paper›PMID 32333974›Full record

ArticleHeart rhythm2020

Small-conductance Ca

Julian Landaw, Zhaoyang Zhang, Zhen Song, Michael B Liu, Riccardo Olcese, Peng-Sheng Chen, James N Weiss, Zhilin Qu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heart rhythm, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Phase 2 Re-Entry Without IJACC. Clinical electrophysiology · 2023
    Trial
  2. Primary Electrical Heart Disease-Principles of Pathophysiology and Genetics.International journal of molecular sciences · 2024
    Review
  3. J wave syndromes: What's new?Trends in cardiovascular medicine · 2022
    Review
  4. Article
  5. Review
  6. The transient outward potassium current plays a key role in spiral wave breakup in ventricular tissue.American journal of physiology. Heart and circulatory physiology · 2021
    Article
  7. Impact of IBiophysical journal · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Julian LandawDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Zhaoyang ZhangDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Zhen SongDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Michael B LiuDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Riccardo OlceseDepartment of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Peng-Sheng ChenKrannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
James N WeissDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Zhilin QuDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California; Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. Electronic address: zqu@mednet.ucla.edu.
University of California, Los Angeles · USIndiana University – Purdue University Indianapolis · US

Funding

Systems in Integrative BiologyT32GM008185 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHOU, TOM · 1987 to 2022
$4.6M
SK Current, beta-3 adrenoceptor activation and Sex Differences in Ventricular ArrhythmogenesisR01HL139829 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI PENG-SHENG CHEN, ZHILIN QU · 2018 to 2026
$4.5M
The Late L-type Ca Current as the Target for a New Class of AntiarrhythmicsR01HL134346 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OLCESE, RICCARDO · 2017 to 2020
$2.3M
A population-based in silico platform for arrhythmia predictionR01HL134709 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI QU, ZHILIN · 2018 to 2021
$1.6M
Triggered arrhythmias induced by heart failure remodeling: A multi-scale computational approachF30HL132449 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LIU, MICHAEL BON-HAO · 2016 to 2019
$163k
Arrhythmogenic Mechanisms in Brugada SyndromeF30HL140864 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LANDAW, JULIAN W · 2018 to 2019
$78k
NHLBI NIH HHS F30 HL132449NHLBI NIH HHS F30 HL140864NHLBI NIH HHS R01 HL134346NHLBI NIH HHS R01 HL134709NHLBI NIH HHS R01 HL139829NIGMS NIH HHS T32 GM008185
6 · The paper itself

Abstract

backgroundSmall-conductance Ca

objectiveThe purpose of this study was to investigate the role of colocalization of SK channels with L-type Ca

methodsWe carried out computer simulations of single-cell and tissue models. SK channels in the model were assigned to preferentially sense Ca

resultsWhen SK channels sense Ca

conclusionColocalization of SK channels with L-type Ca

Indexed as

AnimalsArrhythmias, CardiacDisease Models, AnimalMyocytes, CardiacPotassiumRabbitsSmall-Conductance Calcium-Activated Potassium ChannelsPotassiumSmall-Conductance Calcium-Activated Potassium ChannelsAlternansComputer modelingJ-wave syndromePhase 2 reentrySK channel

Identifiers

PMID32333974
PMCPMC7483665
OpenAlexW3019376852

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.