ArticleSleep2020
Sleep inconsistency between weekends and weekdays is associated with changes in brain function during task and rest.
Article in Sleep, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- From factory floors to dream doors: a systematic review of sleep interventions in industrial workers.BMC public health · 2026Pooled it
- Neuroscience meets behavior: A systematic literature review on magnetic resonance imaging of the brain combined with real-world digital phenotyping.Human brain mapping · 2024Pooled it
- Six nights of sleep extension increases regional cerebral oxygenation without modifying cognitive performance at rest or following acute aerobic exercise.Journal of sleep research · 2022Trial
- Acute sleep rebound following sleep restriction is associated with reduced mortality risk.Nature communications · 2026Article
- Development and Preliminary Psychometric Properties of the Adolescent Sleep Health Belief Scale.Florence Nightingale journal of nursing · 2025Article
- Cortical activation and functional connectivity during verbal fluency task in patients with chronic insomnia: a multi-channel fNIRS study.Scientific reports · 2025Article
- Sleep Stage Monitoring in Congenital Heart Disease (CHD) Using a Digital Health Application Programming Interface (API).Journal of clinical medicine · 2025Article
- Can weekend catch-up sleep repay the sleep debt? Balancing short-term relief with long-term risks.Sleep & breathing = Schlaf & Atmung · 2025Review
- Validation of the Morningness-Eveningness Scale for Children (MESC) with ambulatory circadian monitoring of temperature, light exposure and activity.Journal of sleep research · 2025Article
- Self-Reported Weekend Temporal Eating Patterns of American Adults Differ From Weekday: National Health and Nutrition Examination Surveys: 2015-2020 Prepandemic.Journal of the Academy of Nutrition and Dietetics · 2025Observational
- Enhanced functional connectivity in the reward circuitry in healthy adults with weekend catch-up sleep.Human brain mapping · 2023Article
- Poorer sleep health is associated with altered brain activation during cognitive control processing in healthy adults.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Article
- Differences in Sleep Offset Timing between Weekdays and Weekends in 79,161 Adult Participants in the UK Biobank.Clocks & sleep · 2022Article
- Usability of Smart Home Thermostat to Evaluate the Impact of Weekdays and Seasons on Sleep Patterns and Indoor Stay: Observational Study.JMIR mHealth and uHealth · 2022Observational
- Sleep Patterns and Myopia Among School-Aged Children in Singapore.Frontiers in public health · 2022Article
- Association between Sleep Time and Blood Pressure in Korean Adolescents: Cross-Sectional Analysis of KNHANES VII.Children (Basel, Switzerland) · 2021Article
- Dopamine D1 and D2 receptors are distinctly associated with rest-activity rhythms and drug reward.The Journal of clinical investigation · 2021Article
- Sleep disturbances are associated with cortical and subcortical atrophy in alcohol use disorder.Translational psychiatry · 2021Article
- Evening preference correlates with regional brain volumes in the anterior occipital lobe.Chronobiology international · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
STUDY
objectivesSleep deprivation and circadian disruptions impair brain function and cognitive performance, but few studies have examined the effect of sleep inconsistency. Here, we investigated how inconsistent sleep duration and sleep timing between weekends (WE) and weekdays (WD) correlated with changes in behavior and brain function during task and at rest in 56 (30 female) healthy human participants.
methodsWE-WD differences in sleep duration and sleep midpoint were calculated using 1-week actigraphy data. All participants underwent 3 Tesla blood-oxygen-level-dependent functional Magnetic Resonance Imaging (fMRI) to measure brain activity during a visual attention task (VAT) and in resting-state condition.
resultsWe found that WE-WD inconsistency of sleep duration and sleep midpoint were uncorrelated with each other (r = .08, p = .58) and influenced behavior and brain function differently. Our healthy participants showed relatively small WE-WD differences (WE-WD: 0.59 hours). Longer WE sleep duration (relative to WD sleep duration) was associated with better attentional performance (3-ball: β = .30, t = 2.35, p = .023; 4-ball: β = .30, t = 2.21, p = .032) and greater deactivation of the default mode network (DMN) during VAT (p < .05, cluster-corrected) and greater resting-state functional connectivity (RSFC) between anterior DMN and occipital cortex (p < .01, cluster-corrected). In contrast, later WE sleep timing (relative to WD sleep timing) (WE-WD: 1.11 hours) was associated with worse performance (4-ball: β = -.33, t = -2.42, p = .020) and with lower occipital activation during VAT and with lower RSFC within the DMN.
conclusionsOur results document the importance of consistent sleep timing for brain function in particular of the DMN and provide evidence of the benefits of WE catch-up sleep in healthy adults.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.