Evidence map›Paper›PMID 32333338›Full record

ArticleInternational ophthalmology2020

Optical coherence tomography angiography findings in systemic lupus erythematosus patients with no ocular disease.

Francesco Pichi, Elizabeth Woodstock, Steven Hay, Piergiorgio Neri

Abstract read
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Observational
  17. Article
  18. Current clinical applications of anterior segment optical coherence tomography angiography: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Francesco PichiEye Institute, Cleveland Clinic Abu Dhabi, P.O. Box 112412, Al Maryah Island, Abu Dhabi, UAE. ilmiticopicchio@gmail.com.
Elizabeth WoodstockEye Institute, Cleveland Clinic Abu Dhabi, P.O. Box 112412, Al Maryah Island, Abu Dhabi, UAE.
Steven HayEye Institute, Cleveland Clinic Abu Dhabi, P.O. Box 112412, Al Maryah Island, Abu Dhabi, UAE.
Piergiorgio NeriEye Institute, Cleveland Clinic Abu Dhabi, P.O. Box 112412, Al Maryah Island, Abu Dhabi, UAE.
Cleveland Clinic · USCleveland Eye Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRetinal manifestations are present in 10% of patients with systemic lupus erythematosus (SLE) and consist of vascular changes that can be sight-threatening. Optical coherence tomography angiography (OCTA) is a novel imaging modality that detects movement inside the blood vessels without dye injection and transforms this movement into an angiographic map. The aim of this study is to describe subclinical vessels changes in the eyes of patients with SLE but no retinal manifestations.

methodsIn this cross-sectional study, 15 patients with SLE but no clinical ophthalmic manifestations were scanned through OCTA of the iris and at the level of the macula. Qualitative aspects of the iris vessels, and measure of the foveal avascular zone (FAZ) and vessel density were compared to a cohort of 15 normal controls.

resultsPatients with SLE, even in the absence of ophthalmic manifestations, present a qualitative increase in the iris vessels flow, and enlargement of the FAZ (0.22 ± 0.12 mm DISCUSSION: OCTA can be used in a noninvasive way to detect subclinical vascular changes in patients with SLE. How this information will influence the follow-up and management of these cases will require further prospective studies with a collaborative effort between ophthalmologists and rheumatologists.

Indexed as

Lupus Erythematosus, SystemicTomography, Optical CoherenceCross-Sectional StudiesFluorescein AngiographyFovea CentralisFundus OculiHumansProspective StudiesRetinal VesselsIris vesselsOptical coherence tomography angiographyRetinal vesselsSystemic lupus erythematosus

Identifiers

PMID32333338
OpenAlexW3019040052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.