Evidence map›Paper›PMID 32333291›Full record

SynthesisCanadian journal of anaesthesia = Journal canadien d'anesthesie2020

Effect of early cognitive interventions on delirium in critically ill patients: a systematic review.

Kirsten Deemer, Karolina Zjadewicz, Kirsten Fiest, Stephanie Oviatt, Michelle Parsons, Brittany Myhre, Juan Posadas-Calleja

2 registry-linked trialsOpen access · bronzeAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03604809 nacompletednot on this map

Guided Occupational Therapist Cognitive Interventions in Critically Ill Patients

TypeinterventionalSponsorAlberta Health Services, CalgaryRan2019 to 2020Enrolled70ConditionsDeliriumArmsOT Guided Cognitive Interventions
NCT06115863 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Early Cognitive Stimulation Interventions on Delirium Among Critically Ill Patients

TypeinterventionalSponsorDamanhour UniversityRan2023 to 2025Enrolled130ConditionsDeliriumArmsEarly Cognitive Stimulation Interventions
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Review
  8. Prevention of Delirium in the Intensive Care Unit through Nonpharmacological Interventions: An Umbrella Review.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  9. Brain Prehabilitation for Oncologic Surgery.Current oncology reports · 2022
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kirsten DeemerDepartment of Critical Care Medicine, Alberta Health Services, Calgary, AB, Canada.
Karolina ZjadewiczAlberta Health Services, Calgary, AB, Canada.
Kirsten FiestDepartment of Critical Care Medicine, Alberta Health Services, Calgary, AB, Canada.
Stephanie OviattAlberta Health Services, Calgary, AB, Canada.
Michelle ParsonsDepartment of Critical Care Medicine, Alberta Health Services, Calgary, AB, Canada.
Brittany MyhreAlberta Health Services, Calgary, AB, Canada.
Juan Posadas-CallejaDepartment of Critical Care Medicine, Alberta Health Services, Calgary, AB, Canada. jgposada@ucalgary.ca.
Alberta Health Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA systematic review of the literature was conducted to determine the effects of early cognitive interventions on delirium outcomes in critically ill patients. SOURCE: Search strategies were developed for MEDLINE, EMBASE, Joanna Briggs Institute, Cochrane, Scopus, and CINAHL databases. Eligible studies described the application of early cognitive interventions for delirium prevention or treatment within any intensive care setting. Study designs included randomized-controlled trials, quasi-experimental trials, and pre/post interventional trials. Two reviewers independently extracted data and assessed risk of bias using Cochrane methodology. PRINCIPAL

findingsFour hundred and four citations were found. Seven full-text articles were included in the final review. Six of the included studies had an overall serious, high, or critical risk of bias. After application of cognitive intervention protocols, a significant reduction in delirium incidence, duration, occurrence, and development was found in four studies. Feasibility of cognitive interventions was measured in three studies. Cognitive stimulation techniques were described in the majority of studies.

conclusionThe study of early cognitive interventions in critically ill patients was identified in a small number of studies with limited sample sizes. An overall high risk of bias and variability within protocols limit the utility of the findings for widespread practice implications. This review may help to promote future large, multi-centre trials studying the addition of cognitive interventions to current delirium prevention practices. The need for robust data is essential to support the implementation of early cognitive interventions protocols.

Indexed as

Critical IllnessDeliriumCognitionHumansIncidenceIntensive Care UnitsCognitive interventionsDeliriumDelirium preventionICU deliriumOcupational therapist

Identifiers

PMID32333291
PMCPMC7222136
OpenAlexW3017638515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.