ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021
A pilot study to determine if left ventricular activation time is a useful parameter for left bundle branch capture: Validated by ventricular mechanical synchrony with SPECT imaging.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Efficacy and safety of left bundle branch pacing compared with left ventricular septal pacing: A systematic review and meta-analysis.Heart rhythm O2 · 2025Article
- Relationship Between Electrical Parameters and Cardiac Synchrony in Patients Underwent Left Bundle Branch Area Pacing.Pacing and clinical electrophysiology : PACE · 2024Article
- The Emerging Role of Left Bundle Branch Area Pacing for Cardiac Resynchronisation Therapy.Arrhythmia & electrophysiology review · 2023Review
- Left bundle branch potential predicts better electrical synchrony in bradycardia patients receiving left bundle branch pacing.BMC cardiovascular disorders · 2022Article
- Left Bundle Pacing: Has Cardiac Pacing Changed Forever?Arquivos brasileiros de cardiologia · 2022Article
- Criteria for differentiating left bundle branch pacing and left ventricular septal pacing: A systematic review.Frontiers in cardiovascular medicine · 2022Review
- Mid-term feasibility, safety and outcomes of left bundle branch pacing-single center experience.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeft bundle branch (LBB) pacing has emerged as a novel pacing modality. Left ventricular activation time (LVAT) was reported to be associated with the activation via LBB, but the value of LVAT for determining LBB pacing was unknown. We conducted a pilot study to determine if LVAT could define LBB capture by validating left ventricular (LV) mechanical synchrony.
methodsWe analyzed LVAT in 68 bradycardia-indicated patients who received LBB pacing. LVAT was measured from the stimulus to R-wave peak in lead V5 and V6. LV mechanical synchrony assessed by SPECT MPI was compared according to the value of LVAT and the presence of LBB potential.
resultsThe mean LVAT was 75.4 ± 12.7 ms. LBB potential was recorded in 47 patients (69.1%). Patients with LVAT < 76 ms had better LV mechanical synchrony than those with LVAT ≥ 76 ms. Patients with LVAT < 76 ms or LBB potential had better mechanical synchrony than those with LVAT ≥ 76 ms and no potential. LVAT < 76 ms could predict the normal synchrony with a sensitivity of 88.9% and a specificity of 87.5%.
conclusionA short LVAT indicated favorable mechanical synchrony in SPECT imaging. LVAT < 76 ms might be a practical parameter for defining LBB capture.
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