Evidence map›Paper›PMID 32333223›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2020

Activity of temocillin and comparators against urinary Escherichia coli and Klebsiella pneumoniae from Iran.

Mohammad Rahbar, Sébastien Van de Velde, Parisa Eslami, Masoud Mardani

Abstract readLetter
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 64% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Mohammad RahbarDepartment of Microbiology, Milad Hospital, Tehran, Iran.
Sébastien Van de VeldeMedical Affairs, Eumedica S.A, Chemin de Nauwelette 1, 7170, Manage, Belgium. s.vandevelde@eumedica.com.ORCID https://orcid.org/0000-0001-8901-3104
Parisa EslamiDepartment of Microbiology, Milad Hospital, Tehran, Iran.
Masoud MardaniInfectious Disease and Tropical Medicine Research Center, Shahid Beheshti Medical University, Tehran, Iran.
Milad Hospital · IRNeumedicines (United States) · USShahid Beheshti University of Medical Sciences · IR

Funding

Behbod Daru na
6 · The paper itself

Abstract

To evaluate the ground susceptibility of urinary Escherichia coli and Klebsiella pneumoniae to temocillin, the susceptibility of temocillin and comparators against 500 clinical isolates (231 E. coli and 269 K. pneumoniae) was tested. Temocillin was either found as the most active antibiotic (susceptibility rate of 92%) or the fourth most active antibiotic (65%), as per its urinary and systemic breakpoint, respectively. No difference of activity was observed in isolates expressing ESBL/AmpC enzymes. Considering the percentage of isolates expressing beta-lactamases and the need to spare broad-spectrum antibiotics, temocillin seems promising for treating urinary tract infections.

Indexed as

Anti-Bacterial AgentsEscherichia coliEscherichia coli InfectionsFemaleHumansIranKlebsiella InfectionsKlebsiella pneumoniaeMaleMicrobial Sensitivity TestsMiddle AgedPenicillinsUrinary Tract InfectionsAnti-Bacterial AgentsPenicillinstemocillinEscherichia coliIranKlebsiella pneumoniaeTemocillin

Identifiers

PMID32333223
OpenAlexW3019776029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.