Evidence map›Paper›PMID 32333222›Full record

ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2020

The genetic sequence, origin, and diagnosis of SARS-CoV-2.

Huihui Wang, Xuemei Li, Tao Li, Shubing Zhang, Lianzi Wang, Xian Wu, Jiaqing Liu

Open access · bronzeAbstract readReview
In one paragraph

Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 234 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
234citing papers in PubMed, 5 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

234 citing papers in PubMed, 5 syntheses or guidelines pooled it, 504 citations in OpenAlex.

  1. Traumatic CSF rhinorrhea associated with COVID-19 testing: a case series and systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  2. Pooled it
  3. Recent advances in the diagnosis of COVID-19: a bird's eye view.Expert review of molecular diagnostics · 2021
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Review
  7. Article
  8. In Silico Analysis of CMolecules (Basel, Switzerland) · 2025
    Article
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  13. Review
  14. Development of an intestinal mucosaJournal of virology · 2024
    Article
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174 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Huihui WangDepartment of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Xuemei LiDepartment of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Tao LiDepartment of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. limedical1974@126.com.
Shubing ZhangDepartment of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Lianzi WangDepartment of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Xian WuDepartment of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Jiaqing LiuDepartment of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
First Affiliated Hospital of Anhui Medical University · CNAnhui Medical University · CN

Funding

Natural Science Foundation of China 30801088Natural Science Foundation of China 81201488Natural Science Foundation of China 81571572
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a new infectious disease that first emerged in Hubei province, China, in December 2019, which was found to be associated with a large seafood and animal market in Wuhan. Airway epithelial cells from infected patients were used to isolate a novel coronavirus, named the SARS-CoV-2, on January 12, 2020, which is the seventh member of the coronavirus family to infect humans. Phylogenetic analysis of full-length genome sequences obtained from infected patients showed that SARS-CoV-2 is similar to severe acute respiratory syndrome coronavirus (SARS-CoV) and uses the same cell entry receptor, angiotensin-converting enzyme 2 (ACE2), as SARS-CoV. The possible person-to-person disease rapidly spread to many provinces in China as well as other countries. Without a therapeutic vaccine or specific antiviral drugs, early detection and isolation become essential against novel Coronavirus. In this review, we introduced current diagnostic methods and criteria for the SARS-CoV-2 in China and discuss the advantages and limitations of the current diagnostic methods, including chest imaging and laboratory detection.

Indexed as

Clinical Laboratory TechniquesAlanine TransaminaseAnimalsAntibodies, ViralBetacoronavirusChinaChiropteraCoronavirusCoronavirus Envelope ProteinsCoronavirus InfectionsCoronavirus Nucleocapsid ProteinsCoronavirus RNA-Dependent RNA PolymeraseCOVID-19COVID-19 TestingCOVID-19 VaccinesC-Reactive ProteinAlanine TransaminaseAntibodies, ViralCoronavirus Envelope ProteinsCoronavirus Nucleocapsid ProteinsCoronavirus RNA-Dependent RNA PolymeraseCovid-19 aAPC vaccineCOVID-19 VaccinesC-Reactive ProteinCytokinesenvelope protein, SARS-CoV-2FerritinsFibrin Fibrinogen Degradation Productsfibrin fragment DImmunoglobulin GL-Lactate DehydrogenaseNSP12 protein, SARS-CoV-2nucleocapsid phosphoprotein, SARS-CoV-2Nucleocapsid ProteinsORF1ab polyprotein, SARS-CoV-2PhosphoproteinsPolyproteinsRNA-Dependent RNA PolymeraseSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Viral Envelope ProteinsViral Nonstructural ProteinsViral ProteinsCOVID-19DiagnosisOriginSARS-CoV-2

Identifiers

PMID32333222
PMCPMC7180649
OpenAlexW3018037557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.