ArticleScientific reports2020
Sensory neuroprosthesis improves postural stability during Sensory Organization Test in lower-limb amputees.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 64 citations in OpenAlex.
- Trends in neuroprosthetic technologies to restore sensations.Biomedical engineering letters · 2026Review
- Decoding phantom limb movements from intraneural recordings.Nature communications · 2026Article
- Multi-Level Perception Systems in Fusion of Lifeforms: Classification, Challenges and Future Conceptions.Sensors (Basel, Switzerland) · 2026Review
- Using EMG Biofeedback to Restore Closed-Loop Neural Control on a Powered Prosthetic Ankle.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Toward Natural Limb Function: A New Era in Prosthetic Innovation.Annals of neurology · 2025Review
- Characterizing spinal reflexes evoked by sensory spinal cord stimulation in people with lower-limb amputation.Journal of neuroengineering and rehabilitation · 2025Article
- Impact of Long-Term Home and Community Use of a Lower Limb Sensory Neuroprosthesis.Research square · 2025Article
- xDev: a mixed-signal, software-defined neurotechnology interface platform for accelerated system development.Journal of neural engineering · 2025Article
- The Next Frontier in Neuroprosthetics: Integration of Biomimetic Somatosensory Feedback.Biomimetics (Basel, Switzerland) · 2025Review
- A sensory neuroprosthesis enhances recovery from treadmill-induced stumbles for individuals with lower limb loss.Scientific reports · 2025Article
- Somatosensory restoration and neural control strategies in lower-limb prostheses.npj biomedical innovations · 2025Review
- The effects of neuron morphology and spatial distribution on the selectivity of dorsal root ganglion stimulation.Journal of neural engineering · 2024Article
- Clinical Applications and Future Translation of Somatosensory Neuroprostheses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Sensory integration for neuroprostheses: from functional benefits to neural correlates.Medical & biological engineering & computing · 2024Review
- Restoration of sensory feedback from the foot and reduction of phantom limb pain via closed-loop spinal cord stimulation.Nature biomedical engineering · 2024Article
- Continuous neural control of a bionic limb restores biomimetic gait after amputation.Nature medicine · 2024Article
- Proportional sway-based electrotactile feedback improves lateral standing balance.Frontiers in neuroscience · 2024Article
- Ethics and Governance of Neurotechnology in Africa: Lessons From AI.JMIR neurotechnology · 2024Article
- Sensory Restoration for Improved Motor Control of Prostheses.Current opinion in biomedical engineering · 2023Article
- The impact of walking on the perception of multichannel electrotactile stimulation in individuals with lower-limb amputation and able-bodied participants.Journal of neuroengineering and rehabilitation · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To maintain postural stability, unilateral lower-limb amputees (LLAs) heavily rely on visual and vestibular inputs, and somatosensory cues from their intact leg to compensate for missing somatosensory information from the amputated limb. When any of these resources are compromised, LLAs exhibit poor balance control compared to able-bodied individuals. We hypothesized that restoring somatosensation related to the missing limb via direct activation of the sensory nerves in the residuum would improve the standing stability of LLAs. We developed a closed-loop sensory neuroprosthesis utilizing non-penetrating multi-contact cuff electrodes implanted around the residual nerves to elicit perceptions of the location and intensity of plantar pressures under the prosthetic feet of two transtibial amputees. Effects of the sensory neuroprosthesis on balance were quantified with the Sensory Organization Test and other posturographic measures of sway. In both participants, the sensory neuroprosthesis improved equilibrium and sway when somatosensation from the intact leg and visual inputs were perturbed simultaneously. One participant also showed improvement with the sensory neuroprosthesis whenever somatosensation in the intact leg was compromised via perturbations of the platform. These observations suggest the sensory feedback elicited by neural stimulation can significantly improve the standing stability of LLAs, particularly when other sensory inputs are depleted or otherwise compromised.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.