ReviewCurrent opinion in pediatrics2020
Renal replacement therapies for infants and children in the ICU.
Review in Current opinion in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of bioimpedance-defined overhydration parameters on mortality and cardiovascular events in patients undergoing dialysis: a systematic review and meta-analysis.The Journal of international medical research · 2021Pooled it
- An epidemiological assessment of hemodialysis, continuous kidney replacement therapy, and peritoneal dialysis in pediatric acute kidney injury patients.Renal failure · 2026Article
- Procalcitonin kinetics in critically ill children: impact of continuous kidney replacement therapy modality and dose.Pediatric nephrology (Berlin, Germany) · 2026Observational
- Kidney Support Therapy: Recent Advances.Indian journal of pediatrics · 2026Review
- Pediatric Dialysis: From Acute Kidney Injury to Chronic Renal Replacement Therapies: Challenges and Perspectives in Resource-Limited Countries.Diseases (Basel, Switzerland) · 2026Review
- Tunnelled dialysis catheter tract haemorrhage during mechanical thrombectomy of right atrial line-associated thrombus and line removal: a case report.CVIR endovascular · 2025Article
- Quantifying "Medical Renal Disease": A Pediatric Pilot Study Using Ultrasound Radiomics for Differentiating Acute Kidney Injury and Chronic Kidney Disease.Diagnostics (Basel, Switzerland) · 2025Article
- Innovation of a Neonatal Peritoneal Dialysis Catheter to Expand Dialysis Capabilities for Critically Ill Neonates in Low-Resource Settings.Blood purification · 2025Article
- Addressing challenges in pediatric thrombosis: a comprehensive guideline development.Frontiers in pediatrics · 2025Review
- Continuous Kidney Replacement Therapy in Pediatric Intensive Care Unit: Little People, Big Gaps.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024Article
- Dialysis for paediatric acute kidney injury in Cape Town, South Africa.Pediatric nephrology (Berlin, Germany) · 2024Article
- Acute kidney injury: the experience of a tertiary center of Pediatric Nephrology.Jornal brasileiro de nefrologia · 2024Observational
- Long-term kidney follow-up after pediatric acute kidney support therapy for children less than 15 kg.Pediatric nephrology (Berlin, Germany) · 2023Article
- Safety and efficacy of continuous renal replacement therapy for children less than 10 kg using standard adult machines.European journal of pediatrics · 2023Article
- Peritoneal Dialysis Catheter Placement in Children: Initial Experience with a "2+1"-Port Laparoscopic-Assisted Technique.Medicina (Kaunas, Lithuania) · 2023Article
- Acute Kidney Injury in Very Low Birth Weight Infants: A Major Morbidity and Mortality Risk Factor.Children (Basel, Switzerland) · 2023Article
- Frequency of Acute Kidney Injury and Association With Mortality Among Extremely Preterm Infants.JAMA network open · 2022Article
- Panax notoginseng saponins alleviate damage to the intestinal barrier and regulate levels of intestinal microbes in a rat model of chronic kidney disease.Renal failure · 2022Article
- Management and outcomes of acute post-streptococcal glomerulonephritis in children.World journal of nephrology · 2022Review
- Characteristics of continuous venovenous hemodiafiltration in the acute treatment of inherited metabolic disorders.Pediatric nephrology (Berlin, Germany) · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
purpose of reviewPediatric acute kidney injury (AKI) in critically ill patients is associated with increased morbidity and mortality. Emerging data support that the incidence of pediatric AKI in the ICU is rising. For children with severe AKI, renal replacement therapy (RRT) can provide a lifesaving supportive therapy. The optimal timing to deliver and modality by which to deliver RRT remain a point of discussion within pediatric (and adult) literature. This review discusses the use of RRT for pediatric patients in the ICU. We discuss the most recent evidence-based methods for RRT with a focus on continuous RRT. RECENT
findingsThe feasibility of dialyzing the smallest infants and more medically complex children in the ICU is dependent on the advancements in dialysis access and circuit technology. At present, data indicate that upward of 27% of children in the ICU develop AKI and 6% require RRT. Newer dialysis modalities including prolonged intermittent hemodialysis and continuous flow peritoneal dialysis as well as newer dialysis technologies such as the smaller volume circuits (e.g., Cardio-Renal Pediatric Dialysis Emergency Machine, Newcastle Infant Dialysis and Ultrafiltration System) have made the provision of dialysis safer and more effective for pediatric patients of a variety of sizes. SUMMARY: Renal replacement in the ICU requires a multidisciplinary team approach that is facilitated by a pediatric nephrologist in conjunction with intensivists and skilled nursing staff. Although mortality rates for children on dialysis remain high, outcomes are improving with the support of the multidisciplinary team and dialysis technology advancements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.