Evidence map›Paper›PMID 32332108›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Bmi1 Maintains the Self-Renewal Property of Innate-like B Lymphocytes.

Michihiro Kobayashi, Yang Lin, Akansha Mishra, Chris Shelly, Rui Gao, Colton W Reeh, Paul Zhiping Wang, Rongwen Xi, Yunlong Liu, Pamela Wenzel and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. B1 Cells for Life.Immunological reviews · 2026
    Review
  2. A distinct TCRiScience · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Sex Influences Age-Related Changes in Natural Antibodies and CD5Journal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Michihiro KobayashiCenter for Stem Cell Research and Regenerative Medicine, Institute for Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Yang LinWells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202.
Akansha MishraWells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202.ORCID 0000-0003-3574-5777
Chris ShellyWells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202.
Rui GaoWells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202.
Colton W ReehCenter for Stem Cell Research and Regenerative Medicine, Institute for Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.ORCID 0000-0002-5927-903X
Paul Zhiping WangCenter for Computational Biology and Bioinformatics, Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202.
Rongwen XiNational Institute of Biological Science, Beijing 102206, China.
Yunlong LiuCenter for Computational Biology and Bioinformatics, Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202.ORCID 0000-0002-2699-626X
Pamela WenzelCenter for Stem Cell Research and Regenerative Medicine, Institute for Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Eliver GhosnDepartment of Medicine, Lowance Center for Human Immunology, Emory Vaccine Center, Emory University, Atlanta, GA 30322; and.ORCID 0000-0001-7258-906X
Yan LiuWells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202; liu219@iu.edu Momoko.Yoshimoto@uth.tmc.edu.
Momoko YoshimotoCenter for Stem Cell Research and Regenerative Medicine, Institute for Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030; liu219@iu.edu Momoko.Yoshimoto@uth.tmc.edu.ORCID 0000-0002-7272-6682
Indiana University – Purdue University Indianapolis · USInstitute for Molecular Medicine · USEmory University · USNational Institute of Biological Sciences, Beijing · CN

Funding

Biomechanical Determinants of Hematopoietic Stem Cell PotentialR01DK111599 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI PAMELA LYNN WENZEL · 2018 to 2026
$4.2M
Embryonic origin and self-renewal of B-1a cellsR01AI121197 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI YOSHIMOTO, MOMOKO · 2016 to 2020
$1.9M
Embryonic origin and self-renewal of B-1a cellsR56AI110831 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI YOSHIMOTO, MOMOKO · 2015 to 2015
$390k
NIAID NIH HHS R01 AI121197NIAID NIH HHS R56 AI110831NIDDK NIH HHS R01 DK111599
6 · The paper itself

Abstract

The self-renewal ability is a unique property of fetal-derived innate-like B-1a lymphocytes, which survive and function without being replenished by bone marrow (BM) progenitors. However, the mechanism by which IgM-secreting mature B-1a lymphocytes self-renew is poorly understood. In this study, we showed that

Indexed as

AnimalsB-Lymphocyte SubsetsBone MarrowCell LineageCell ProliferationCells, CulturedCellular MicroenvironmentHematopoietic Stem CellsLymphocytesLymphopoiesisMiceMice, Inbred C57BLMice, Inbred NODMice, SCIDPolycomb Repressive Complex 1Proto-Oncogene ProteinsBmi1 protein, mousePolycomb Repressive Complex 1Proto-Oncogene Proteins

Identifiers

PMID32332108
PMCPMC7293378
OpenAlexW3017622528

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.